Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
库存:
100
宿主:
Goat
靶点:
Human USP9X. This antibody is expected to recognize isoform 3 (NP_001034679.2)
抗体名:
DFFRX, FAM, USP9
规格:
50 μg
分子量:
292kDa
细胞定位:
Antigen Cellular Localization:Cytoplasm. Cell projection, growth cone.
形式:
Liquid
参考文献:
Jones M.H.,et al.Hum. Mol. Genet. 5:1695-1701(1996).Jones M.H.,et al.Hum. Mol. Genet. 6:334-335(1996).Ross M.T.,et al.Nature 434:325-337(2005).Yu W.,et al.Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases.Rush J.,et al.Nat. Biotechnol. 23:94-101(2005).
产品概述:
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality USP9X / FAM antibody.
功能:
Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important role regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both 'Lys-29'- and 'Lys-33'-linked polyubiquitins chains. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Involved in axonal growth and neuronal cell migration.
总结:
Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important role regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both 'Lys-29'- and 'Lys-33'-linked polyubiquitins chains. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Involved in axonal growth and neuronal cell migration.
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