Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
克隆性:
单克隆
库存:
100
宿主:
Mouse
靶点:
A synthetic peptide containing amino acid residues 96-113 of human kB-Ras1.
抗体名:
KBRAS1
规格:
50 μg
分子量:
22kDa
细胞定位:
Antigen Cellular Localization:Cytoplasm.
形式:
Liquid
参考文献:
Fenwick C.,et al.Science 287:869-873(2000).Ota T.,et al.Nat. Genet. 36:40-45(2004).Chen Y.,et al.J. Biol. Chem. 278:23101-23106(2003).Chen Y.,et al.Mol. Cell. Biol. 24:3048-3056(2004).
产品概述:
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality NKIRAS1 antibody (aa96-113, clone 184C278).
功能:
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
总结:
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
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