Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
库存:
100
宿主:
Rabbit
靶点:
Human DUSP26. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
抗体名:
DUSP24, LDP4, MKP8, NATA1, SKRP3
规格:
50 μg
分子量:
24kDa
细胞定位:
Antigen Cellular Localization:Cytoplasm. Nucleus. Golgi apparatus.
形式:
Liquid
参考文献:
Vasudevan S.A.,et al.Biochem. Biophys. Res. Commun. 330:511-518(2005).Yu W.,et al.Oncogene 26:1178-1187(2007).Takagaki K.,et al.Mol. Cell. Biochem. 296:177-184(2007).Zama T.,et al.Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.Ota T.,et al.Nat. Genet. 36:40-45(2004).
产品概述:
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality MKP-8 / DUSP26 antibody (C-Terminus).
功能:
Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).
总结:
Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK).
联系方式: