Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
克隆性:
单克隆
库存:
100
宿主:
mouse
靶点:
PPOX (AAH02357, 378 a.a. ~ 477 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
规格:
100 μg
分子量:
50765 Da
细胞定位:
形式:
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
参考文献:
1.Methotrexate enhances 5-aminolevulinic acid-mediated photodynamic therapy-induced killing of human SCC4 cells by upregulation of coproporphyrinogen oxidase.Yang DF, Lee JW, Chen HM, Huang Z, Hsu YCJ Formos Med Assoc. 2014 Jan 29. pii: S0929-6646(13)00452-X. doi: 10.1016/j.jfma.2013.12.005.2.Posttranslational stability of the heme biosynthetic enzyme ferrochelatase is dependent on iron availability and intact iron-sulfur cluster assembly machinery.Crooks DR, Ghosh MC, Haller RG, Tong WH, Rouault TA.Blood. 2010 Jan 28;115(4):860-9. Epub 2009 Nov 25.
产品概述:
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality PPOX antibody (monoclonal) (M01).
功能:
总结:
This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.
联系方式: