Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
克隆性:
单克隆
库存:
100
宿主:
mouse
靶点:
PCDH10 (NP_065866, 18 a.a. ~ 127 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
规格:
100 μg
分子量:
112936 Da
细胞定位:
形式:
Clear, colorless solution in phosphate buffered saline, pH 7.2 .
参考文献:
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.High-resolution melting analysis of PCDH10 methylation levels in gastric, colorectal and pancreatic cancers. Yu B, et al. Neoplasma, 2010. PMID 20353276.Field methylation silencing of the protocadherin 10 gene in cervical carcinogenesis as a potential specific diagnostic test from cervical scrapings. Wang KH, et al. Cancer Sci, 2009 Nov. PMID 19709077.Protocadherin PCDH10, involved in tumor progression, is a frequent and early target of promoter hypermethylation in cervical cancer. Narayan G, et al. Genes Chromosomes Cancer, 2009 Nov. PMID 19681120.Pioneers in the ventral telencephalon: The role of OL-protocadherin-dependent striatal axon growth in neural circuit formation. Hirano S. Cell Adh Migr, 2007 Oct. PMID 19262141.
产品概述:
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality PCDH10 antibody (monoclonal) (M07).
功能:
总结:
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The mRNA encodes a cadherin-related neuronal receptor thought to play a role in the establishment and function of specific cell-cell connections in the brain. This family member contains 6 extracellular cadherin domains, a transmembrane domain and a cytoplasmic tail differing from those of the classical cadherins. Alternatively spliced transcripts encode isoforms with unique cytoplasmic domains.
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