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- 详细信息
- 文献和实验
- 技术资料
- 靶点:
Protein disulfide-isomerase A6, Endoplasmic reticulum protein 5, ER protein 5, ERp5, Protein disulfide isomerase P5, Thioredoxin domain-containing protein 7, PDIA6, ERP5, P5, TXNDC7
- 浓度:
Affinity Purification
- 应用范围:
WB, IHC-P, FC, IF
- 宿主:
Rabbit
- 适应物种:
H, M, Rat
- 保质期:
1-2年
- 供应商:
安诺伦(北京)生物科技有限公司
- 克隆性:
Polyclonal
- 保存条件:
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
- 形态:
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原:
This PDIA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-172 amino acids from the Central region of human PDIA6.
- 规格:
400 µl/200 µl/100 µl/50 µl
| 规格: | 400 µl | 产品价格: | ¥5000.0 |
|---|---|---|---|
| 规格: | 200 µl | 产品价格: | ¥3250.0 |
| 规格: | 100 µl | 产品价格: | ¥2250.0 |
| 规格: | 50 µl | 产品价格: | ¥1375.0 |
细胞定位:Endoplasmic reticulum lumen. Cell membrane. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545)
功能:May function as a chaperone that inhibits aggregation of misfolded proteins (PubMed:12204115). Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling (PubMed:24508390). May also regulate the UPR via the EIF2AK3 UPR sensor (PubMed:24508390). Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin (PubMed:15466936).
总结:Tissue Location: Expressed in platelets (at protein level).
稀释方法:IHC-P--1:100 IF--1:100 WB--1:1000 IHC-P--1:100~500 FC--1:10~50
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文献和实验secondary antibody review -- data from 99 publications
cytometry used as a control to detect cell responses targeted antigen 7 Alexa Fluor 488 7 Cy3 8 goat IgG Alexa Fluor 488 1:2000 detect antibody binding in human embryonic kidney 293T cells Invitrogen 9 donkey
Localization of rDNA at Nucleolar Structural Components by Immunoelectron Microscopy
locate rDNA in the nucleolar ultrastructural components such as the fibrillar center (FC), dense fibrillar component (DFC), and granular component (GC). In situ hybridization at the electron microscopic level is suitable for localization of rDNA
一、文献 1. Chen, H.H., J. Lebon, and A.D. Riggs, Analysis of RNA structure and RNA-protein interactions in mammalian cells by use of terminal transferase-dependent PCR. Methods Mol Biol, 2008. 488: p. 319-41. 2. Terzi, L.C. and G.G. Simpson
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