- $495
- Leading Biology
- United States
- APR11114G
- 2025年08月27日
- Rabbit
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
400-429 aa
- 亚型：
Rabbit Ig
- 保存条件：
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 库存：
100
- 宿主：
Rabbit
- 靶点：
This HERV (ERVWE1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-429 amino acids from the Central region of human HERV (ERVWE1).
- 抗体名：
ERVWE1
- 规格：
100 μl
59866 Da
细胞定位：
Antigen Cellular Localization: Transmembrane protein: Cell membrane; Single-pass type I membrane protein Syncytin-1: Virion.
形式：
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
参考文献：
Oluwole,S.O., Amyotroph Lateral Scler 8 (2), 67-72 (2007) Gong,R., Cell. Physiol. Biochem. 20 (5), 517-526 (2007) Antony,J.M., AIDS Res. Hum. Retroviruses 22 (12), 1253-1259 (2006)
产品概述：
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HERV (ERVWE1) antibody (Center).
功能：
This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5 (PubMed:10708449, PubMed:12050356, PubMed:23492904).
总结：
Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. The protein, also known as syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. This protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.
联系方式：
生物商城：http://www.annoron.com
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官方售后：400-965-8633
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文献和实验Double immunohistochemistry for BCL6 and PNA for Germinal Center detection.
(see Reagents and Solutions). 3- incubate with the blocking for 10 min. If one of your antibody is biotin-conjugated, you need at this point to do endogenous biotin blocking. 4- blot the slides without washing and apply the primary antibody, in a moist
Double immunohistochemistry for BCL6 and PNA for Germinal Center detection
Double immunohistochemistry for BCL6 and PNA for Germinal Center detection. (on fixed, paraffin-embedded sections) Cut sections at 4µm, use a clean water bath with distilled water, and let the sections dry
with those with a postgerminal center/activated profile. Microarray technology may not be available in many diagnostic laboratories, and antibody-based methods are much simpler and cheaper and are therefore more applicable to the routine setting. Immunocytochemistry
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