- ￥1375 - 5000
- Leading Biology
- APR06990G
- 美国
- 2025年08月26日
- WB, IHC-P, FC
- Rabbit
- H, M
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![MYL7 Mouse Monoclonal Antibody [Clone ID: LBI5D2]](https://img1.dxycdn.com/2022/0707/344/1496323853485278553-14.jpg!wh200)
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- 详细信息
- 文献和实验
- 技术资料
- 靶点：
Beclin-1, Coiled-coil myosin-like BCL2-interacting protein, Protein GT197, BECN1, GT197
- 浓度：
Affinity Purification
- 应用范围：
WB, IHC-P, FC
- 宿主：
Rabbit
- 适应物种：
H, M
- 保质期：
1-2年
- 供应商：
安诺伦（北京）生物科技有限公司
- 克隆性：
Polyclonal
- 保存条件：
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
- 形态：
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原：
This Beclin 1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-239 amino acids from human Beclin 1.
- 规格：
400ul/200 µl/100 µl/50ul
| 规格： | 400ul | 产品价格： | ￥5000.0 |
|---|---|---|---|
| 规格： | 200 µl | 产品价格： | ￥3250.0 |
| 规格： | 100 µl | 产品价格： | ￥2250.0 |
| 规格： | 50ul | 产品价格： | ￥1375.0 |
细胞定位：Cytoplasm {ECO:0000250|UniProtKB:O88597, ECO:0000269|PubMed:19713971, ECO:0000269|PubMed:21364619}. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Mitochondrion membrane; Peripheral membrane protein. Endosome {ECO:0000250|UniProtKB:O88597} Cytoplasmic vesicle, autophagosome. Note=Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells (By similarity) {ECO:0000250|UniProtKB:O88597, ECO:0000269|PubMed:19050071} [Beclin-1-C 37 kDa]: Mitochondrion {ECO:0000250|UniProtKB:O88597}
功能：Plays a central role in autophagy (PubMed:18570871, PubMed:21358617, PubMed:23184933, PubMed:23974797, PubMed:28445460). Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530, PubMed:23974797, PubMed:26783301). Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. Involved in endocytosis (PubMed:25275521). Protects against infection by a neurovirulent strain of Sindbis virus (PubMed:9765397). May play a role in antiviral host defense.
总结：Tissue Location: Ubiquitous.
稀释方法：WB--1:4000 WB--1:1000 IHC-P--1:100~500 FC--1:10~50
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文献和实验Interaction Trap/Two‐Hybrid System to Identify Interacting Proteins
of interest Plasmids (see Table 4.4.1 ): e.g., pEG202 (Fig. ), pSH18‐34 (Fig. ), pSH17‐4, pRFHM1 Yeast strain: e.g., EGY48 (ura3 trp1 his3 3LexA ‐operator‐LEU2 ; see Table
Immunoglobulin Structure Home Page http://www.path.cam.ac.uk/~mrc7/mikeimages.htmlOverview of immunoglobulin structure and function, with many images of computer-rendered three-dimensional molecular models. V BASE — The Database of Human Antibody Genes
[资源] 所有的看家基因(housekeeping genes)列表+引物设计服务
NM_004515 Homo sapiens interleukin enhancer binding factor 2, 45kDa (ILF2), mRNA 1000 NM_004651 Homo sapiens ubiquitin specific protease 11 (USP11), mRNA 1950 NM_004888 Homo sapiens ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G isoform
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