- ￥1375 - 5000
- Leading Biology
- AMM07062G
- 美国
- 2025年08月25日
- WB, IHC-P
- Rabbit
- H
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- 详细信息
- 技术资料
- 靶点：
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A, PDE8A
- 浓度：
Affinity Purification
- 应用范围：
WB, IHC-P
- 宿主：
Rabbit
- 适应物种：
H
- 保质期：
1-2年
- 供应商：
安诺伦（北京）生物科技有限公司
- 克隆性：
Polyclonal
- 保存条件：
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
- 形态：
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- 免疫原：
This PDE8A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 557-587 amino acids from the Central region of human PDE8A.
- 规格：
400 µl/200 µl/100 µl/50 µl
| 规格： | 400 µl | 产品价格： | ￥5000.0 |
|---|---|---|---|
| 规格： | 200 µl | 产品价格： | ￥3250.0 |
| 规格： | 100 µl | 产品价格： | ￥2250.0 |
| 规格： | 50 µl | 产品价格： | ￥1375.0 |
功能：Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:18983167). May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development (PubMed:18983167). Binding to RAF1 reduces RAF1 'Ser-259' inhibitory- phosphorylation and stimulates RAF1-dependent EGF-activated ERK- signaling (PubMed:23509299). Protects against cell death induced by hydrogen peroxide and staurosporine (PubMed:23509299).
总结：Tissue Location: Expressed in most tissues except thymus and peripheral blood leukocytes. Highest levels in testis, ovary, small intestine and colon
稀释方法：WB--1:1000 IHC-P--1:100~500
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