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- 详细信息
- 文献和实验
- 技术资料
- 靶点:
Corticotropin-releasing factor receptor 2, CRF-R-2, CRF-R2, CRFR-2, Corticotropin-releasing hormone receptor 2, CRH-R-2, CRH-R2, CRHR2, CRF2R, CRH2R
- 浓度:
Affinity Purification
- 应用范围:
WB, IHC-P, FC
- 宿主:
Rabbit
- 适应物种:
H
- 保质期:
1-2年
- 供应商:
安诺伦(北京)生物科技有限公司
- 克隆性:
Polyclonal
- 保存条件:
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
- 形态:
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原:
This CRFR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from human CRFR2.
- 规格:
400 µl/200 µl/100 µl/50 µl
| 规格: | 400 µl | 产品价格: | ¥5000.0 |
|---|---|---|---|
| 规格: | 200 µl | 产品价格: | ¥3250.0 |
| 规格: | 100 µl | 产品价格: | ¥2250.0 |
| 规格: | 50 µl | 产品价格: | ¥1375.0 |
细胞定位:Cell membrane; Multi-pass membrane protein
功能:G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.
稀释方法:WB--1:1000 IHC-P--1:100~500 FC--1:10~50
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文献和实验在于遗传背景稳定,操作方便且经济。RA 模型大致可分为诱导型和转基因型两大类,本文将针对这两大类模型进行总结和比较,以便广大学者为自己的研究选择合适的 RA 模型。 一、诱导型类风湿关节炎模型 目前,最常见的诱导型类风湿关节炎模型包括佐剂诱导关节炎(Adjuvant arthritis,AA)、胶原诱导的关节炎(Collagen-induced Arthritis, CIA)、胶原抗体诱导的关节炎(Collagen antibody-induced Arthritis, CAIA)以及其他的药物
Interaction Trap/Two‐Hybrid System to Identify Interacting Proteins
of interest Plasmids (see Table 4.4.1 ): e.g., pEG202 (Fig. ), pSH18‐34 (Fig. ), pSH17‐4, pRFHM1 Yeast strain: e.g., EGY48 (ura3 trp1 his3 3LexA ‐operator‐LEU2 ; see Table
Immunoglobulin Structure Home Page http://www.path.cam.ac.uk/~mrc7/mikeimages.htmlOverview of immunoglobulin structure and function, with many images of computer-rendered three-dimensional molecular models. V BASE — The Database of Human Antibody Genes
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