Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
适应物种:
Human
库存:
100
宿主:
Rabbit
应用范围:
WB, IHC-P, E
靶点:
This AKAP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-36 amino acids from the N-terminal region of human AKAP4.
抗体名:
AKAP82
规格:
100 μl
分子量:
94477 Da
细胞定位:
Antigen Cellular Localization:Cell projection, cilium, flagellum. Note=Localizes to the principle piece of the sperm flagellum
形式:
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
参考文献:
Moretti, E., et al. Asian J. Androl. 9(5):641-649(2007)Lefievre, L., et al. Proteomics 7(17):3066-3084(2007)Ross, M.T., et al. Nature 434(7031):325-337(2005)Brown, P.R., et al. Biol. Reprod. 68(6):2241-2248(2003)Ficarro, S., et al. J. Biol. Chem. 278(13):11579-11589(2003)
产品概述:
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.This product is a high quality AKAP4 antibody (N-term).
功能:
Major structural component of sperm fibrous sheath. Plays a role in sperm motility.
总结:
The A-kinase anchor proteins (AKAPs) are a group ofstructurally diverse proteins, which have the common function ofbinding to the regulatory subunit of protein kinase A (PKA) andconfining the holoenzyme to discrete locations within the cell.This gene encodes a member of the AKAP family. The encoded proteinis localized to the sperm flagellum and may be involved in theregulation of sperm motility. Alternative splicing of this generesults in two transcript variants encoding different isoforms.
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