Protein phosphatase 1A, Protein phosphatase 2C isoform alpha, PP2C-alpha, Protein phosphatase IA, PPM1A, PPPM1A
浓度:
Affinity Purification
应用范围:
WB
宿主:
Rabbit
适应物种:
H
保质期:
1-2年
供应商:
安诺伦(北京)生物科技有限公司
克隆性:
Polyclonal
保存条件:
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
形态:
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原:
This PPM1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 355-382 amino acids from human PPM1A.
规格:
400 µl/200 µl/100 µl/50 µl
规格:
400 µl
产品价格:
¥5000.0
规格:
200 µl
产品价格:
¥3250.0
规格:
100 µl
产品价格:
¥2250.0
规格:
50 µl
产品价格:
¥1375.0
分子量:42448
细胞定位:Nucleus. Cytoplasm, cytosol. Membrane; Lipid- anchor Note=Weakly associates at the membrane and N-myristoylation mediates the membrane localization. {ECO:0000250|UniProtKB:P49443}
功能:Enzyme with a broad specificity. Negatively regulates TGF- beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha- mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.