- $545
- Leading Biology
- United States
- AMM05537G
- 2025年08月17日
- WB
- Rabbit
- Human, Mouse, Rat
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
- 克隆性：
单克隆
- 适应物种：
Human, Mouse, Rat
- 库存：
100
- 宿主：
Rabbit
- 应用范围：
WB
- 靶点：
A synthetic peptide corresponding to residues in the extracellular region of human Acetylcholine receptor subunit beta was used as an immunogen.
- 抗体名：
ACHRB, CHRNB
- 规格：
100 μl
56698 Da
细胞定位：
Antigen Cellular Localization: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
形式：
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
参考文献：
1. Miyazawa A, et al. Nature 423(6943):949-55, 2003
2. Hill JA, et al. J Neurosci 13: 1551-68, 1993
产品概述：
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ACHR-beta antibody (extracellular).
功能：
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
总结：
The nicotinic acetylcholine receptor controls electrical signaling between nerve and muscle cells by opening and closing a gated, membrane-spanning pore. The gate is a constricting hydrophobic girdle at the middle of the lipid bi-layer, formed by weak interactions between neighboring inner helices. When acetylcholine enters the ligand-binding domain, it triggers rotations of the protein chains on opposite sides of the entrance to the pore (1). The widespread distribution of the beta subunit suggests it may serve as a common subunit in different AChR combinations in various brain regions. Regulation of the expression of beta subunit appears to be relatively unrestrained, with an apparent excess of protein synthesized in the cytoplasm relative to that which ultimately arrives at functional targets in the plasma membrane (2).
联系方式：
生物商城：http://www.annoron.com
办公电话：010-56256916
官方售后：400-965-8633
企业 QQ：3212874516、3198592576
地 址：北京经济技术开发区永昌中路4号院4号楼3层
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Anticardiolipin Antibody and Anti-beta 2 Glycoprotein I Antibody Assays
) antibodies and anti-beta 2 glycoprotein I (β2-GPI) antibodies. Other autoantibodies, such as those directed against anionic phospholipids, can also be assayed; however they are not of clinical significance. Participation in a quality assurance
. Cells are embedded within capture antibody-containing agarose and stimulated under conditions of interest. Extracellularly released cytokine is captured within the matrix at the point of release from the cell and can be labeled with a fluorochrome
。 如果beta-catenin抗体不好使，或者EGFP太大影响定位的话，还可以构建Flag标签类载体，转染细胞，加入药物，用抗Flag抗体免疫荧光检测，荧光显微镜下观察就好了。 wangjh28 但按照事先的推测，处理了以后会下调该基因的表达 我觉得科学不能有事先的推测的结果，这样容易受思维定势的影响，而忽略了新发现 dongreyuan 我打算用SAB的β-catenin（Ab-37）Antibody，说明
技术资料暂无技术资料 索取技术资料
