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- 文献和实验
- 技术资料
- 库存:
244
- 英文名:
Recombinant Human Interleukin-1 alpha
- 保质期:
长期
- 供应商:
北京百奥莱博科技有限公司
- 保存条件:
冷冻(-20℃)
- 规格:
2μg
特别提示:包括重组人IL-1α在内,本公司的所有产品仅可用于科研实验,严禁用于临床医疗及其他非科研用途!
产品名称:重组人IL-1α
英文名称:Recombinant Human Interleukin-1 alpha
产品货号:GS4360
产品规格:2μg
分子量:Approximately 18.0kDa,a single non-glycosylated polypeptide chain containing 159 amino acids.
储存条件:冷冻(-20℃)
概述
Interleukin-1 alpha(IL-1α)is a non-secreted proinflammatory cytokine produced mainly by activated macrophages,as well as neutrophils,epithelial cells,and endothelial cells.It possesses metabolic,physiological,haematopoietic activities,and plays one of the central roles in the regulation of the immune responses.Both IL-1α and IL-1β binds to the same receptor and has similar identical biological properties.Among various species,the amino acid sequence of mature IL-1α is conserved 60%to 70%and human IL-1 has been found to be biologically active on murine cell lines.IL-1α recently started to find effective application in cosmetic and dermatological formulations,which allow to significantly harmonizing derma architecture.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | >97%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 1.0pg/ml,corresponding to a specific activity of>1.0×109 IU/mg. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4. |
| 内毒素 | Less than 1.0 EU/μg of rHuIL-1α as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | SAPFSFLSNV KYNFMRIIKY EFILNDALNQ SIIRANDQYL TAAALHNLDE AVKFDMGAYK SSKDDAKITV ILRISKTQLY VTAQDEDQPV LLKEMPEIPK TITGSETNLL FFWETHGTKN YFTSVAHPNL FIATKQDYWV CLAGGPPSIT DFQILENQA |
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