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文献和实验The Concept of Multiple-Target Anti-miRNA Antisense Oligonucleotide Technology
as an miRNA therapy for human disease such as cancer and cardiac disorders. This technology was developed by my research laboratory in collaboration with Yang’s group (Lu et al., Nucleic Acids Res 37:e24–e33, 2009), and it is similar but distinct
Experimental Applications: Human Acetylcholinesterase as a Model Nervous System Protein
A DNA sequence encoding the brain and muscle form of human AChE (AChE-T) was constructed in our laboratory from cloned cDNA and genomic sequences, and tentatively identified by its homology to known ChEs (Soreq et al., 1990). This putative
Introduction of human 14-3-3 proteins
The human and bovine 14-3-3 eta protein mRNAs are highly conservedEvolutionary conservation of the 14-3-3 proteinExpression and structural analysis of 14-3-3 proteinsCrystal structure of the zeta isoform of the 14-3-3 proteinStructure of a 14
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