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- 2025年11月05日
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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 供应商：
上海觅拓
- 规格：
1L
描述
CTS AIM V SFM is supplemented with L-glutamine, streptomycin sulfate, and gentamicin sulfate. Additional supplementation with cytokines per specific procedure is necessary and should be carried out aseptically immediately prior to use.
Features include:
• Used as ancillary reagent in Provenge™ (sipuleucel-T), the first therapeutic cancer vaccine approved by the FDA [1]
• Accommodates multiple culture formats, including culture flasks, WAVE bags, and G-Rex devices
• Supports T-cell activation using Dynabeads magnetic beads and stimulatory antibody- and antigen-presenting cell protocols
• Supports expansion of gene-modified CAR T cells (lentiviral transduction)
• Manufactured in conformity with cGMP for medical devices
Proven use
CTS AIM V SFM for research use only is based on the same formulation as our therapeutic-grade CTS AIM V SFM, which was the first FDA-cleared, therapeutic-grade, commercial SFM in the U.S. used in adoptive immunotherapy applications. CTS AIM V SFM is used as an ancillary reagent in Provenge™ (sipuleucel-T), the first therapeutic cancer vaccine approved by the FDA.
GMP manufactured
The primary manufacturing site for CTS AIM V SFM is FDA-registered and has an ISO13485-certified quality management system. The methods and controls used for the manufacturing are in conformity with current Good Manufacturing Practices for medical devices, 21 CFR Part 820. Alternate manufacturing sites are available, providing risk mitigation by helping to ensure security of supply.
Versatility
CTS AIM V SFM has been widely adopted in clinical research applications including the culture of CAR T, polyclonal T, natural killer, dendritic, and TIL cells. CTS AIM V SFM accommodates multiple culture formats, including culture flasks, WAVE™ bags, and G-Rex™ devices. CTS AIM V SFM was designed to support expansion of cultured human immune cells when supplemented with either human AB serum or CTS Immune Cell SR.
What you get
CTS AIM V SFM is available in a 1-liter bottle for small volume users as well as a 10-liter bag for larger volume users. Full traceability documentation such as Certificate of Origin, Certificate of Analysis, and Drug Master File are available.
1. Madan RA, Gulley JL. Sipuleucel-T: harbinger of a new age of therapeutics for prostate cancer. Expert Rev Vaccines. 2011 Feb;10(2):141-50.
规格
| Other Additives: | HSA (Human Serum Albumin) |
|---|---|
| Product Line: | AIM V™, CTS™ |
| Product Size: | 1 liter |
| Shipping Condition: | Room Temperature |
内容及储存
Store at 2–8°C; protect from light
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文献和实验实验原理 Dynabeads® CD3⁄CD28 CTS™ offer a simple method for isolation, activation and expansion of human T cells. Firstly, CD3 T cells are separated and concentrated from the apheresis product by magnetic cell separation
Differentiating Neural Stem Cells into Neurons and Glial Cells
d. Remove the vessel from the incubator and store it until use. Immediately before use, remove all CELLStart™ CTS® solution and replace it with complete StemPro® NSC SFM. 2) Coating Culture Vessels with Geltrex™ a. Thaw
相关专题 无血清培养基产品选择指南 Serum-free media(SFM) 技术介绍 1、含血清成分培养体系的劣势 培养动物细胞，无论是为了增殖病毒，还是为了获得相关的生物制品，都力求使细胞大规模、高密度生长，并在高密度下维持高的细胞活性，简化下游纯化工艺，提高生物制品的安全性和产率，降低产品的成本，提高市场竞争力。但是常规细胞培养 基的组分——血清的存在严重制约了动物细胞的规模培养，使用户不得不每次
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