CCL25 is new member of CC family chemokine.It is also called Thymus-expressed chemokine(TECK)because it is restricted produced by thymus and intestine.Especially,the dendritic cells derived from thymus but not bone marrow had identified to be the source of CCL25.By binding with CCR9,it elicits its effects of chemotactic for thymocytes,macrophages,and dendritic cells.Additionally,CCL25 takes part in regulating the development of T-cells.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
外观
Sterile Filtered White lyophilized(freeze-dried)powder.
纯度
>95%by SDS-PAGE and HPLC analyses.
来源
Escherichia coli.
生物活性
Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 5.0-50ng/ml.
成分
Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,150 mM NaCl.
内毒素
Less than 1 EU/μg of rMuTECK/CCL25 as determined by LAL method.
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.