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- 详细信息
- 技术资料
- 保存条件:
4°C, protect from light
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
40456-50-6
- 规格:
1 mg/5 mg
| 规格: | 1 mg | 产品价格: | ¥2400.0 |
|---|---|---|---|
| 规格: | 5 mg | 产品价格: | ¥5950.0 |
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Yatein
CAS No. : 40456-50-6
MCE 国际站:Yatein
产品活性:Yatein 是从 A. chilensis 中提取的木质素,具有抗增殖活性。Yatein 能通过中断立早基因的表达,抑制单纯疱疹病毒 1 型 (HSV-1) 的复制。
研究领域:Anti-infection | Apoptosis
In Vitro: Yatein induces cell-cycle arrest at G2/M phase (5 μM; 24 hours) and enhances G2/M phase-related protein expression (5 μM; 6-12 hours) in human lung adenocarcinoma A549 and CL1-5 cells.
Yatein (5 μM; 6-12 hours) induces DNA damage through activation of the ATM/ATR pathway in human A549 and CL1-5 cells.
Yatein (5 μM; 6 hours) affects microtubule dynamics by inhibiting tubulin polymerization.
In Vivo: Yatein (20 mg/kg; i.p.; five times per week; for 42 days) exhibits in vivo antitumor effects in a human lung adenocarcinoma xenograft mouse model.
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