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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
4°C, sealed storage, away from moisture
- 英文名:
BC-3781 acetate
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
1350636-82-6
- 规格:
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥2798.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥1066.0 |
| 规格: | 5 mg | 产品价格: | ¥2240.0 |
| 规格: | 10 mg | 产品价格: | ¥3360.0 |
| 规格: | 25 mg | 产品价格: | ¥6700.0 |
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Lefamulin acetate
CAS No. : 1350636-82-6
MCE 国际站:Lefamulin acetate
产品活性:Lefamulin (BC-3781) acetate 是一种具有口服活性的抗生素 (antibiotic)。Lefamulin acetate 通过与 50S 细菌核糖体的肽基转移酶 peptidyl transferase 中心结合来抑制蛋白质合成。Lefamulin acetate 具有抗炎活性。Lefamulin acetate 可用于研究细菌感染,如细菌性肺炎。
研究领域:Anti-infection
作用靶点:Bacterial | Antibiotic
In Vitro: Lefamulin (0-1 mg/L) acetate shows inhibitory activity against C. trachomatis, N. gonorrhoeae, and M. genitalium.
Lefamulin acetate shows potent activity against all M. pneumoniae strains with MIC values of ≤0.008 μg/mL.
In Vivo: Lefamulin (10-140 mg/kg, s.c.) acetate shows anti-inflammatory effect on LPS-induced lung neutrophilia mouse model.
Lefamulin (1.25-160 mg/kg, s.c.) acetate shows antibacterial effect in S. pneumoniae or S. aureus challenged lung infection mice.
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Sodium Acetate Precipitation of Small Nucleic Acids
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Acetate Kinase From Methanosarcina thermophila, a Key Enzyme for Methanogenesis
Materials and procedures are described for the overproduction and purification of acetate kinase from Methanosarcina thermophila. Methods are detailed for large-scale preparation of the unaltered enzyme and for overproduction and one-step
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