产品货号:jlcR23713 英文名称 :Cux2 中文名称 :转录同源蛋白质CUX2抗体 别 名 :CDP2; Cut like homeobox 2; Cut-like 2; CUTL2; CUX2; Homeobox protein cut-like 2; Homeobox protein cux 2; Homeobox protein Cux-2; KIAA0293; CUX2_HUMAN. 研究领域 :神经生物学 信号转导 干细胞 转录调节因子 表观遗传学 抗体来源 :Rabbit 克隆类型 :Polyclonal 交叉反应 :Human, Mouse, Rat, Chicken, Pig, Sheep, 产品应用 :WB=1:500-2000 ELISA=1:500-1000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分 子 量 : 162kDa 细胞定位 :细胞核 性 状 : Lyophilized or Liquid 浓 度 :1mg/ml 免 疫 原 :KLH conjugated synthetic peptide derived from human Cux2:601-700/1486 亚 型 :IgG 纯化方法 :affinity purified by Protein A 储 存 液 :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 :Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed :PubMed 产品介绍 : Cux2 is a marker for cortical subpopulations. Cux2 is an orthologue of the Drosophila cut gene, which encodes a homeodomain protein involved in neuronal specification. During cortical development Cux2 identifies two subpopulations with different spatial origins, migratory behaviours and phenotypic characteristics: (i) a population of interneurons, which invades the pallium from the subpallium; and (ii) a neuronal population produced in the pallium around embryonic day 11.5, which divides in the SVZ and accumulates in the intermediate zone (IZ). Subsequently, Cux2 is a marker of upper cortical layers.
Function: May be a transcription factor involved in neural specification. Binds to DNA in a sequence-specific manner
Subcellular Location: Nuclear
Similarity: Belongs to the CUT homeobox family. Contains 3 CUT DNA-binding domains. Contains 1 homeobox DNA-binding domain.
SWISS: O14529
Gene ID: 23316
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.