产品货号:jlcR17347 英文名称:HNRPUL1 中文名称:异质核核糖核蛋白U样蛋白1抗体 别 名:Adenovirus early region 1B associated protein 5; Adenovirus early region 1B-associated protein 5; E130317O14Rik; E1B 55 kDa associated protein 5; E1B AP5; E1B-55 kDa-associated protein 5; E1B-AP5; E1BAP5; fb53d10; fk45c03; FLJ12944; Heterogeneous nuclear ribonucleoprotein U-like protein 1; HNRL1_HUMAN; Hnrnpul1; HNRPUL1; MGC36621; MGC78330; wu:fb53d10; wu:fk45c03; zgc:85971. 研究领域:细胞生物 转录调节因子 结合蛋白 表观遗传学 抗体来源:Rabbit 克隆类型:Polyclonal 交叉反应: Human, Mouse, Rat, Cow, Horse, Cat, 产品应用:WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分 子 量:96kDa 细胞定位:细胞核 性 状:Lyophilized or Liquid 浓 度:1mg/ml 免 疫 原:KLH conjugated synthetic peptide derived from human HNRPUL1:701-800/856 亚 型:IgG 纯化方法:affinity purified by Protein A 储 存 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed:PubMed 产品介绍:This gene encodes a nuclear RNA-binding protein of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. This protein binds specifically to adenovirus E1B-55kDa oncoprotein. It may play an important role in nucleocytoplasmic RNA transport, and its function is modulated by E1B-55kDa in adenovirus-infected cells. Two transcript variants encoding different isoforms have been found for this gene. Additional variants have also been found, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008]
Function: Acts as a basic transcriptional regulator. Represses basic transcription driven by several virus and cellular promoters. When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand-stimulation. Plays also a role in mRNA processing and transport. Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro.
Subcellular Location: Nucleus.
Post-translational modifications: Methylated.
Similarity: Contains 1 B30.2/SPRY domain. Contains 1 SAP domain.
SWISS: Q9BUJ2
Gene ID: 11100
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.