重组小鼠MIP-1α/CCL3北京厂家

特别提示：包括重组小鼠MIP-1α/CCL3在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组小鼠MIP-1α/CCL3
英文名称：Recombinant Murine Macrophage Inflammatory Protein-1 alpha/CCL3
产品货号：GS4729
产品规格：2μg

分子量：Approximately 7.9kDaprotein containing 69 amino acid residues,including the four highly conserved cysteine residues present in CC chemokines.
储存条件：冷冻（-20℃）

概述

CCL3,also known as macrophage inflammatory protein-1α(MIP-1α),is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes.Studies showed CCL3 can bind to CCR1,CCR4 and CCR5.MIP-1α can induce a dose-dependent inhibition of different strains of HIV-1,HIV-2,and simian immunodeficiency virus(SIV).Recombinant murine MIP-1α is a 7.9kDaprotein containing 69 amino acid residues,including the four highly conserved cysteine residues present in CC chemokines and it shares approximately 71%and 91%amino acid sequence homology with the human and rat protein.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞98%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The biological activity determined by a chemoattract bioassay using murine splenocytes is in a concentration range of 10-100ng/ml.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 30%Acetonitrile and 0.1%TFA.
内毒素	Less than 0.1 EU/μg of rMuMIP-1α/CCL3 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	APYGADTPTA CCFSYSRKIP RQFIVDYFET SSLCSQPGVI FLTKRNRQIC ADSKETWVQE YITDLELNA

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