产品货号 : jlcR12305 英文名称 : USE1 中文名称 : 囊泡转运蛋白Use1抗体 别 名 : 2010315L10Rik; 5730403H22Rik; AV002165; D12; Ed2; Embryonic development factor 2; MDS032; P31; Protein D12; Protein p31; putative MAPK activating protein PM26; Putative MAPK-activating protein PM26; Q-snare; RGD1306660; SLT1; SNARE-like tail-anchored protein 1 homolog; Unconventional SNARE in the ER 1 homolog (S. cerevisiae); Unconventional SNARE in the ER 1 homolog; Use1; USE1 like protein; Use1 unconventional SNARE in the ER 1 homolog (S. cerevisiae); USE1-like protein; USE1_HUMAN; USE1L; Vesicle transport protein USE1. 研究领域 : 发育生物学 信号转导 干细胞 转录调节因子 抗体来源 : Rabbit 克隆类型 : Polyclonal 交叉反应 : Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, 产品应用 : WB=1500-2000 ELISA=1500-1000 IHC-P=1400-800 IHC-F=1400-800 ICC=1100-500 IF=1100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutionsconcentrations should be determined by the end user. 分 子 量 : 29kDa 细胞定位 : 细胞浆 细胞膜 性 状 : Lyophilized or Liquid 浓 度 : 1mgml 免 疫 原 : KLH conjugated synthetic peptide derived from human USE1151-259259 亚 型 : IgG 纯化方法 : affinity purified by Protein A 储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 : Store at -20 癈 for one year. Avoid repeated freezethaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈. PubMed : PubMed 产品介绍 : In eukaryotic cells, the Golgi apparatus receives newly synthesized proteins from the endoplasmic reticulum (ER) and, after covalent modification, delivers them to their destination in the cell. For membrane-directed proteins this process is believed to be carried out via vesicular transport. Correct vesicular transport is determined by specific pairing of vesicle-associated SNAREs (v-SNAREs) with those on the target membrane (t-SNAREs). Unconventional SNARE in the ER 1, also known as USE1 or protein p31, is a 259 amino acid t-SNARE that forms a larger complex with ZW10, RINT-1 and Syntaxin 18. Upon Mg2+-AP treatment in the presence of NSF and SNAP, ZW10, RINT-1 and USE1 dissociate from Syntaxin 18. USE1 is a single-pass type IV membrane protein that is localized to the endoplasmic reticulum membrane. Three named isoforms exist for USE1 as a result of alternative splicing events.
Function SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.
Subunit Component of a SNARE complex consisting of STX18, USE1L, BNIP1SEC20L and SEC22B. Interacts directly with STX18.