产品货号:jlcR18298 英文名称 :LIPT1 中文名称 : 硫辛酰连接酶抗体 别 名 :Lipoate biosynthesis protein; Lipoate-protein ligase; Lipoyl ligase; Lipoyltransferase 1; Lipoyltransferase 1 mitochondrial; LIPT_HUMAN; Lipt1; mitochondrial. 研究领域 :细胞生物 免疫学 信号转导 转录调节因子 新陈代谢 线粒体 抗体来源 :Rabbit 克隆类型 :Polyclonal 交叉反应 : Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, 产品应用 :ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分 子 量 :41kDa 细胞定位 :细胞浆 线粒体 性 状 : Lyophilized or Liquid 浓 度 :1mg/ml 免 疫 原 :KLH conjugated synthetic peptide derived from human LIPT1:101-200/373 亚 型 :IgG 纯化方法 :affinity purified by Protein A 储 存 液 :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 :Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed : PubMed 产品介绍:The process of transferring lipoic acid to proteins is a two-step process. The first step is the activation of lipoic acid by lipoate-activating enzyme to form lipoyl-AMP. For the second step, the protein encoded by this gene transfers the lipoyl moiety to apoproteins. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 13. Read-through transcription also exists between this gene and the neighboring downstream mitochondrial ribosomal protein L30 (MRPL30) gene. [provided by RefSeq, Mar 2011]
Function: Catalyzes the transfer of the lipoyl group from lipoyl-AMP to the specific lysine residue of lipoyl domains of lipoate-dependent enzymes.
Subcellular Location: Mitochondrion.
Tissue Specificity: Highly expressed in skeletal muscle and heart, moderately in kidney and pancreas, and detected at lower levels in liver, brain, placenta and lung.
Similarity: Belongs to the lplA family.
SWISS: Q9Y234
Gene ID: 51601
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.