产品货号:jlcR16721 英文名称:TRIM 中文名称:T淋巴细胞受体相互作用分子抗体 别 名:HSPC062; pp29/30; T cell receptor interacting molecule; T-cell receptor-associated transmembrane adapter 1; T-cell receptor-interacting molecule; TCRIM; TRAT1; TRAT1_HUMAN; TRIM. 研究领域:细胞生物 免疫学 信号转导 淋巴细胞 t-淋巴细胞 抗体来源:Rabbit 克隆类型:Polyclonal 交叉反应:Human, Dog, 产品应用:ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分 子 量:21kDa 细胞定位:细胞膜 性 状:Lyophilized or Liquid 浓 度:1mg/ml 免 疫 原:KLH conjugated synthetic peptide derived from human TRIM:21-120/186 亚 型:IgG 纯化方法:affinity purified by Protein A 储 存 液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed:PubMed 产品介绍Function: Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
Subcellular Location: Cell membrane.
Tissue Specificity: Strongly expressed in thymus, and to a lesser extent in spleen, lymph node and peripheral blood lymphocytes. Present in T-cells and NK cells, but not B-cells (at protein level).
Post-translational modifications: Phosphorylated on tyrosines by LCK or FYN upon TCR activation.
SWISS: Q6PIZ9
Gene ID: 50852
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.