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产品名称：Recombinant Mouse PD-L1/B7-H1/CD274
Known as Programmed cell death 1 ligand 1Cd274; programmed cell death 1 ligand 1;PD-L1;PDCD1 ligand 1;programmed death ligand 1;B7 homolog 1;B7-H1;CD274
Derived from Human cells
Purity Greater than 95% as determined by reducing SDS-PAGE.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Shipping The product is shipped at ambient temperature.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Endotoxin Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Background Mouse Programmed cell death 1 ligand 1(Cd274，PD-L1), is a member of the growing B7 family of immune proteins.It involved in the costimulatory signal essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.B7-H1 has been identified as one of two ligands for programmed death1 (PD1), a member of the CD28 family of immunoreceptors. B7-H1 is constitutively expressed in several organs such as heart, skeletal muscle B7-H1 expression is upregulated in a small fraction of activated T and B cells and a much larger fraction of activated monocytes. The costimulatory function of B7-H1 is critical for enhancing maturation and differentiation of T-cells in lymphoid organs.B7-H1 expression is also induced in dendritic cells and keratinocytes after IFN gamma stimulation. Interaction of B7-H1 with PD1 results in inhibition of TCR-mediated proliferation and cytokine production. The B7-H1:PD1 pathway is involved in the negative regulation of some immune responses and may play an important role in the regulation of peripheral tolerance.
Recombinant Mouse Programmed Cell Death 1 Ligand 1 is produced by our Mammalian expression system and the target gene encoding Phe19-Thr238 is expressed with a 6His tag at the C-terminus.
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用于水产品及食物中毒样品中弧菌特别是副溶血性弧菌的分离和鉴定 特价促销 弧菌显色培养基
每支添加于100ml（CRM008）弧菌显色培养基中。 特价促销 弧菌显色培养基选择性添加剂冻干试剂
用于水产品及食物中毒样品中弧菌特别是副溶血性弧菌的分离和初步鉴别。 特价促销 弧菌显色琼脂培养基平板
每支含环丝氨酸40mg，添加于100mL胰月示－亚酸盐－环丝氨酸琼脂基础(TSC)中 特价促销 环丝氨酸
用于监视干热灭菌效果的常规性芽孢纸条生物指示剂 特价促销 环氧烷/干热灭菌芽孢条
当暴露于高于10kGy剂量的γ辐射中时，γ射线指示标签由黄色变为红色。 特价促销 环氧烷灭菌指示条
ATXN7L1 共济失调蛋白7样1抗体 特价促销
ATXN7L2 共济失调蛋白7样2抗体 特价促销
ATXN7L3B 共济失调7样蛋白3B抗体 特价促销
AU1 tag AU1 tag标签抗体 特价促销
AU5 tag AU5 tag标签抗体 特价促销
AUP1/Ancient ubiquitous protein 1 原始广泛存在蛋白1抗体 特价促销
Aurora A/ARK-1/AURKA 有丝分裂激酶A抗体 特价促销
Aurora A/B/C 有丝分裂激酶A/B/C抗体 特价促销
Aurora B/STK-1 有丝分裂激酶B抗体 特价促销
Aurora C 有丝分裂激酶B抗体 特价促销
NTAL Polyclonal Antibody T-细胞激活连接蛋白家族成员2 抗体
MAL Polyclonal Antibody T细胞成熟相关蛋白 抗体
TLX1 Polyclonal Antibody T细胞白血病同源盒蛋白1 抗体
TLX3 Polyclonal Antibody T细胞白血病同源盒3 抗体
Tcl1 Polyclonal Antibody T-细胞白血病/淋巴瘤蛋白1A 抗体
TBR1 Polyclonal Antibody T脑力盒1 抗体
Recombinant Mouse PD-L1/B7-H1/CD274TBX6 Polyclonal Antibody T-框蛋白6 抗体
TBX21 Polyclonal Antibody T-框蛋白21 抗体
TBX20 Polyclonal Antibody T-框蛋白20 抗体
TBX15 Polyclonal Antibody T框蛋白15 抗体
产品名称：Recombinant Mouse PD-L1/B7-H1/CD274
Known as Programmed cell death 1 ligand 1Cd274; programmed cell death 1 ligand 1;PD-L1;PDCD1 ligand 1;programmed death ligand 1;B7 homolog 1;B7-H1;CD274
Derived from Human cells
Purity Greater than 95% as determined by reducing SDS-PAGE.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Shipping The product is shipped at ambient temperature.
Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Endotoxin Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Background Mouse Programmed cell death 1 ligand 1(Cd274，PD-L1), is a member of the growing B7 family of immune proteins.It involved in the costimulatory signal essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.B7-H1 has been identified as one of two ligands for programmed death1 (PD1), a member of the CD28 family of immunoreceptors. B7-H1 is constitutively expressed in several organs such as heart, skeletal muscle B7-H1 expression is upregulated in a small fraction of activated T and B cells and a much larger fraction of activated monocytes. The costimulatory function of B7-H1 is critical for enhancing maturation and differentiation of T-cells in lymphoid organs.B7-H1 expression is also induced in dendritic cells and keratinocytes after IFN gamma stimulation. Interaction of B7-H1 with PD1 results in inhibition of TCR-mediated proliferation and cytokine production. The B7-H1:PD1 pathway is involved in the negative regulation of some immune responses and may play an important role in the regulation of peripheral tolerance.
Recombinant Mouse Programmed Cell Death 1 Ligand 1 is produced by our Mammalian expression system and the target gene encoding Phe19-Thr238 is expressed with a 6His tag at the C-terminus.
以下是公司正在热销的相关产品：
弧菌的生鉴定 特价促销 弧菌科细菌生鉴定盒（16种×5次）
用于水产品及食物中毒样品中弧菌特别是副溶血性弧菌的分离和鉴定 特价促销 弧菌显色培养基
每支添加于100ml（CRM008）弧菌显色培养基中。 特价促销 弧菌显色培养基选择性添加剂冻干试剂
用于水产品及食物中毒样品中弧菌特别是副溶血性弧菌的分离和初步鉴别。 特价促销 弧菌显色琼脂培养基平板
每支含环丝氨酸40mg，添加于100mL胰月示－亚酸盐－环丝氨酸琼脂基础(TSC)中 特价促销 环丝氨酸
用于监视干热灭菌效果的常规性芽孢纸条生物指示剂 特价促销 环氧烷/干热灭菌芽孢条
当暴露于高于10kGy剂量的γ辐射中时，γ射线指示标签由黄色变为红色。 特价促销 环氧烷灭菌指示条
ATXN7L1 共济失调蛋白7样1抗体 特价促销
ATXN7L2 共济失调蛋白7样2抗体 特价促销
ATXN7L3B 共济失调7样蛋白3B抗体 特价促销
AU1 tag AU1 tag标签抗体 特价促销
AU5 tag AU5 tag标签抗体 特价促销
AUP1/Ancient ubiquitous protein 1 原始广泛存在蛋白1抗体 特价促销
Aurora A/ARK-1/AURKA 有丝分裂激酶A抗体 特价促销
Aurora A/B/C 有丝分裂激酶A/B/C抗体 特价促销
Aurora B/STK-1 有丝分裂激酶B抗体 特价促销
Aurora C 有丝分裂激酶B抗体 特价促销
NTAL Polyclonal Antibody T-细胞激活连接蛋白家族成员2 抗体
MAL Polyclonal Antibody T细胞成熟相关蛋白 抗体
TLX1 Polyclonal Antibody T细胞白血病同源盒蛋白1 抗体
TLX3 Polyclonal Antibody T细胞白血病同源盒3 抗体
Tcl1 Polyclonal Antibody T-细胞白血病/淋巴瘤蛋白1A 抗体
TBR1 Polyclonal Antibody T脑力盒1 抗体
Recombinant Mouse PD-L1/B7-H1/CD274TBX6 Polyclonal Antibody T-框蛋白6 抗体
TBX21 Polyclonal Antibody T-框蛋白21 抗体
TBX20 Polyclonal Antibody T-框蛋白20 抗体
TBX15 Polyclonal Antibody T框蛋白15 抗体
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文献和实验相关实验
，PD-1/PD-L1这么值钱，大家一定好奇它到底是什么鬼。 PD-1全名是程序性死亡分子1(programmed death-1)是Ishida等[1]通过消减杂交技术于1992年发现的[2]，是CD28家族成员，胞质区含有2个酪氨酸残基，1个位于靠近N端的免疫受体酪氨酸抑制基序(ITIM)中，另一个1个位于靠近C端的免疫受体酪氨酸转化基序(ITSM)中[2]。 PD-L1(CD274)是B7家族成员，是PD-1的配体，属于1型跨膜蛋白，全长290个氨基酸，包含1个IgV样
with a Ca2+ -free medium or with trypsin/dispase. The latter facilitates the introduction of recombinant or trappable probes and microimaging studies of, for example, changes in cytosolic-free Ca2+ concentration or the dynamics of individual organelles
Purification of Recombinant Poly(ADP-Ribose) Polymerases
, more than 11 mg of pure and highly active mouse PARP-2 can be obtained from 1 L of Sf9 insect cell culture.
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Recombinant Mouse PD-L1/B7-H1/CD274
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