公司供应的产品仅用于科研 产品名称:Recombinant Human EGFR/HER1/ERBB1 Known as Epidermal growth factor receptor;Proto-oncogene c-ErbB-1;Receptor tyrosine-protein kinase erbB-1; EGFR;ERBB; ERBB1; HER1 Derived from Human cells Purity Greater than 95% as determined by reducing SDS-PAGE. Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. Shipping The product is shipped at ambient temperature. Storage Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months Reconstitution Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. Endotoxin Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test. Background The EGFR subfamily of receptor tyrosine kinases is composed of EGFR, ErbB2, ErbB3 and ErbB4. The EGFR shares 43% - 44% aa sequence identity with the ECD of human EGFR subfamily. All these family members are type I transmembrane glycoproteins with an extracellular ligand binding domain. The extracellular ligand binding domain is containing two cysteine-rich domains separated by a spacer region and a cytoplasmic domain containing a membrane-proximal tyrosine kinase domain. Ligand binding could induce EGFR homodimerization and heterodimerization with ErbB2, resulting in cell signaling, heterodimerization tyrosine phosphorylation and kinase activation. It can bind EGF, amphiregulin, TGF-alpha, betacellulin, epiregulin, HB-EGF, epigen, and so on. Its signaling regulates multiple biological functions including cell proliferation, differentiation, motility, and apoptosis. EGFR can also be recruited to form heterodimers with the ligand-activated ErbB3 or ErbB4. EGFR is overexpressed in different tumors. Several anti-cancer drugs use EGFR as target. Recombinant Human Epidermal Growth Factor Receptor is produced by our Mammalian expression system and the target gene encoding Leu25-Ser645 is expressed with a 6His tag at the C-terminus. 以下是公司正在热销的相关产品: 5(6)-羧基荧光素琥珀酰亚胺酯(混合物)5(6)-FAM, SE [5-(and-6)-Carboxyfluorescein, succinimidyl ester] *Mixed isomers* 5-羧基荧光素琥珀酰亚胺酯(单一合物)5-FAM, SE [5-Carboxyfluorescein, succinimidyl ester] *Single isomer* 5-羧基荧光素琥珀酰亚胺酯(单一合物)5-FAM, SE [5-Carboxyfluorescein, succinimidyl ester] *Single isomer* 5-羧基荧光素琥珀酰亚胺酯(单一合物)5-FAM, SE [5-Carboxyfluorescein, succinimidyl ester] *Single isomer* 6-羧基荧光素琥珀酰亚胺酯(单一合物)6-FAM, SE [6-Carboxyfluorescein, succinimidyl ester] *Single isomer* 6-羧基荧光素琥珀酰亚胺酯(单一合物)6-FAM, SE [6-Carboxyfluorescein, succinimidyl ester] *Single isomer* 6-羧基荧光素琥珀酰亚胺酯(单一合物)6-FAM, SE [6-Carboxyfluorescein, succinimidyl ester] *Single isomer* ABCB5 ATP结合蛋白家族5抗体 特价促销 ABCB5 抗體, 兔多抗, 抗原親和純 ABCB6 ATP结合蛋白家族6抗体 特价促销 ABCD1/CCL22 嗜酸粒细胞趋蛋白22抗体 特价促销 ABCE1 核糖核酸酶L抑制蛋白抗体 特价促销 ABCF1 ATP结合盒蛋白家族GCN20F家族1抗体 特价促销 ABCF3 三磷酸腺苷结合盒转运蛋白F亚基3抗体 特价促销 ABCG1 三磷酸腺苷结合盒亚家族G1抗体 特价促销 ABCG2 抗體, 兔多抗, 抗原親和純 ABCG2/CD338 三磷酸腺苷结合转运蛋白G超家族成员2抗体 特价促销 SLPI Polyclonal Antibody 分泌性白细胞肽酶抑制蛋白 抗体 SFRP4 Polyclonal Antibody 分泌型卷曲相关蛋白4 抗体 SFRP3 Polyclonal Antibody 分泌型卷曲相关蛋白3 抗体 SFRP1 Polyclonal Antibody 分泌型卷曲相关蛋白1 抗体 SLUR1 Polyclonal Antibody 分泌型Ly6/uPAR相关蛋白1 抗体 Recombinant Human EGFR/HER1/ERBB1SECR Polyclonal Antibody 分泌素 抗体 SG3A2 Polyclonal Antibody 分泌球蛋白3A成员2 抗体 PA21B Polyclonal Antibody 分泌磷脂酶A2 抗体 OPN Polyclonal Antibody 分泌蛋白1/骨桥蛋白1 抗体 7B2 Polyclonal Antibody 分泌粒蛋白V(7B2蛋白) 抗体