Cell line gene knock-in and kn

Gene Knock In and Knock Out

Omar giving a talk at Hunter college; sorry for the poor quaility bc iSight was not behaving as usual. " Gene Knock In and Knock Out "

Receptor Knock-Out and Knock-In Strategies

and their totipotency to introduce the desired mutation into the endogenous receptor locus. In the second-generation knock-outs using the Cre/loxP system, the disruption of the receptor gene is cell-type specific or region-specific but is irreversible in principle

Receptor Knock-Out and Gene Targeting: Generation of Knock-Out Mice

Until recently, opioid receptors were studied only by a pharmacological approach because agonists and antagonists were the only tools available (1 ). Interpretation of the experimental data was complicated because of the poor selectivity