- 询价
- Cell Signaling Technology
- 3888
- USA
- 2025年07月14日
- W, IF-IC
- Rabbit
- H,Mk
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- 详细信息
- 技术资料
- 抗体英文名：
NuMA Antibody
- 抗原：
synthetic peptide corresponding to residues near the carboxy terminus of human NuMA
- 应用范围：
W, IF-IC
- 宿主：
Rabbit
- 保质期：
详见说明书
- 库存：
大量
- 供应商：
CST
- 适应物种：
H,Mk
- 级别：
详见MSDS文件
- 是否单克隆：
2
- 保存条件：
-20°c
- 规格：
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key: H=Human Mk=Monkey
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Source |
|---|---|---|---|---|
| W IF-IC | H Mk | Endogenous | 238 | Rabbit |
| Protocols |
|
|---|---|
| Specificity / Sensitivity | NuMA Antibody detects endogenous levels of total NuMA protein. |
| Source / Purification | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human NuMA. Western Blotting
Western blot analysis of extracts from various cell types using NuMA Antibody. IF-IC
Confocal immunofluorescent analysis of HeLa cells using NuMA Antibody (green). Actin filaments have been labeled with DY-554 phalloidin (red). Blue pseudocolor = DRAQ5® #4084 (fluorescent DNA dye). |
| Background | The nuclear mitotic apparatus protein (NuMA) is a coiled coil protein involved in the formation and maintenance of the mitotic spindle. NuMA plays a role in chromatin organization during interphase, which influences mammary epithelial differentiation (1,2). During apoptosis, carboxy-terminal cleavage of NuMA may amplify signaling in the cell death pathway (2). NuMA is phosphorylated at numerous sites, with phosphorylation at Ser395 occurring in an ATM/ATR-dependent manner in response to DNA damage (3,4). |
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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