- 询价
- Cell Signaling Technology
- 3143
- USA
- 2025年07月15日
- W, IP, IF-IC
- Rabbit
- H,M,R
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- 详细信息
- 技术资料
- 抗体英文名：
FoxA2/HNF3β Antibody
- 抗原：
synthetic peptide corresponding to a sequence of human FoxA2/HNF3β
- 应用范围：
W, IP, IF-IC
- 宿主：
Rabbit
- 库存：
大量
- 保质期：
详见说明书
- 级别：
详见MSDS文件
- 适应物种：
H,M,R
- 供应商：
CST
- 是否单克隆：
2
- 保存条件：
-20°c
- 规格：
100 ul (10 western blots)/carrier free & custom formulation / quantity
| 规格： | 产品价格： | ￥请询价 | |
|---|---|---|---|
| 规格： | 100 ul (10 western blots) | 产品价格： | ￥请询价 |
| 规格： | carrier free & custom formulation / quantity | 产品价格： | ￥请询价 |
pathway more info application references datasheet PDF MSDS PDF protocols
Applications Key: W=Western Blotting IP=Immunoprecipitation IF-IC=Immunofluorescence (Immunocytochemistry)
Reactivity Key: H=Human M=Mouse R=Rat
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.
| Applications | Reactivity | Sensitivity | MW (kDa) | Source |
|---|---|---|---|---|
| W IP IF-IC | H (M) (R) | Endogenous | 50 | Rabbit |
| Protocols | |
|---|---|
| Specificity / Sensitivity | FoxA2/HNF3β Antibody detects endogenous levels of total FoxA2/HNF3β protein. |
| Source / Purification | Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to a sequence of human FoxA2/HNF3β. Antibodies are purified by Protein A and peptide affinity chromatography. Western Blotting
Western blot analysis of extracts from HepG2 cells using FoxA2/HNF3β Antibody. IF-IC
Confocal immunofluorescent analysis of HepG2 cells using FoxA2/HNF3β Antibody (green). Actin filaments have been labeled with DY-554 phalloidin (red). |
| Background | Forkhead box protein A2 (FoxA2, also known as hepatocyte nuclear factor 3β or HNF3β) is a transcription factor that plays an important role in hepatocyte function (1). FoxA2/HNF3β is required for the activation of hepatic gluconeogenic gene expression during fasting (1). Together with the PGC-1β coactivator, FoxA2/HNF3β stimulates the expression of genes involved in fatty acid β-oxidation and therefore increases fatty acid metabolism (2). FoxA2/HNF3β, along with PGC-1β, also activates the expression of microsomal triacylglycerol transfer protein (MTP) and promotes VLDL secretion (2). In addition to its roles in metabolic syndromes, FoxA2/HNF3β is essential for development of the endoderm and midline structures in mouse embryos (3-5). |
| Application References | Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know ! |
| Companion Products |
For Research Use Only. Not For Use In Diagnostic Procedures. |
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