Ribosomal Protein L7a (R225) Antibody

Ribosomal Protein L7a (R225) A

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  • 询价
  • Cell Signaling Technology已认证
  • USA
  • 2025年11月23日
  • W
  • Rabbit
  • H,M,R,Mk
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    • 详细信息
    • 技术资料
    • 抗体英文名

      Ribosomal Protein L7a (R225) Antibody

    • 抗原

      synthetic peptide corresponding to residues surrounding Arg225 of human ribosomal protein L7a

    • 应用范围

      W

    • 宿主

      Rabbit

    • 保质期

      详见说明书

    • 级别

      详见MSDS文件

    • 适应物种

      H,M,R,Mk

    • 库存

      大量

    • 供应商

      CST

    • 是否单克隆

      2

    • 保存条件

      -20°c

    • 规格

      100 ul (10 western blots)/carrier free & custom formulation / quantity

    规格:产品价格:¥请询价
    规格:100 ul (10 western blots)产品价格:¥请询价
    规格:carrier free & custom formulation / quantity产品价格:¥请询价

    pathway more info application references datasheet PDF MSDS PDF protocols

    Applications Key:  W=Western Blotting
    Reactivity Key:  H=Human  M=Mouse  R=Rat  Mk=Monkey
    Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on 100% sequence homology.

    Applications Reactivity Sensitivity MW (kDa) Source
    W H M R Mk Endogenous 32 Rabbit
    Protocols
    Specificity / Sensitivity

    Ribosomal protein L7a Antibody detects endogenous levels of total ribosomal protein L7a protein. Immunofluorescent staining using this antibody shows ribosomal protein L7a localized mostly on the ER membrane and in nucleoli, sites for translation and ribosome synthesis, respectively, indicating its utility as a ribosomal marker.

    Source / Purification

    Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Arg225 of human ribosomal protein L7a. Antibodies are purified by protein A and peptide affinity chromatography.

    Western Blotting

    Western Blotting

    Western blot analysis of extracts from various cell lines using Ribosomal Protein L7a (R225) Antibody.

    Background

    Ribosomal protein L7a is a highly conserved ribosome protein localized to 60S ribosomal subunit (1). The protein has distinct domains that target the newly synthesized polypeptide to nucleus and the nucleoli, the site of ribosome biosynthesis (2). Ribosomal protein L7a can also interact with RNA in vitro through two distinct RNA-binding domains in the protein (3). Taken together, nucleolar localization and the ability to bind RNA suggests that ribosomal protein L7a may act as an important component for ribosome biosynthesis and function.

    1. De Falco, S. et al. (1993) Gene 126, 227-235.
    2. Russo, G. et al. (1997) J. Biol. Chem. 272, 5229-5235.
    3. Russo, G. et al. (2005) Biochem J. 385, 289-299.
    Application References

    Have you published research involving the use of our products? If so we'd love to hear about it. Please let us know !

    Companion Products

    For Research Use Only. Not For Use In Diagnostic Procedures.

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