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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated sytnthetic peptide encompassing a sequence within the C-term region of human ORAI3.
- 亚型:
mouse IgG1
- 形态:
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.02% sodium azide. Antibody was purified by Protein-A affinity chromatography.
- 保存条件:
Store at 4°C.
- 克隆性:
单克隆
- 标记物:
见下方详细说明
- 适应物种:
H, R
- 保质期:
1-2年
- 抗原来源:
KLH-conjugated sytnthetic peptide encompassing a sequence within the C-term region of human ORAI3.
- 目录编号:
253273
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Mouse
- 应用范围:
E, WB
- 浓度:
见详细说明信息
- 靶点:
ORAI3 (1B4F1)
- 抗体英文名:
ORAI3 (1B4F1) Antibody
- 抗体名:
ORAI3 (1B4F1) Antibody
- 规格:
0.1 mg
ORAI3 (1B4F1) Antibody产品详细介绍:
| 产品名称: | ORAI3 (1B4F1) Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 253273 |
| 规格: | 0.1 mg |
| 产品描述: | Antigen stimulation of immune cells triggers Ca++ entry t hrough Ca++ release-activated Ca++ (CRAC) channels. ORAI3 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. All three homologs have been shown to function as Ca++ plasma membrane channels gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor. However, ORAI3 channels failed to produce detectable Ca++ selective currents in cells co-transfected with ORAI3 and STIM1, indicating that ORAI3 channels undergo a lesser degree of depotentiation than ORAI1 or ORAI2. Na+ currents through ORAI1, 2 and 3 channels were equally inhibited by extracellular Ca++, indicating that each have similar affinities for Ca++ within the selectivity filter. This antibody is predicted to have no cross-reactivity to ORAI1 or ORAI2. Larger molecular weight bands are sometimes seen in SDS-PAGE; these may represent post-translationally modified ORAI 3. |
| 克隆类型: | Mouse Monoclonal Antibody |
| 亚型: | mouse IgG1 |
| 免疫原: | KLH-conjugated sytnthetic peptide encompassing a sequence within the C-term region of human ORAI3. |
| 适用物种: | H, R |
| 应用范围: | E, WB |
| 应用说明: | E: 1:500-1:1,000; WB: 1:100-1:500 |
| 别名: | ORAI3; Transmembrane protein 142C; TMEM142C; Calcium release-activated calcium channel protein 3 |
| 形态: | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.02% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存条件: | Store at 4°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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