- ￥3000 - 3999
- Abbiotec
- 美国
- 253254
- 2025年11月10日
- E, WB
- Mouse
- H, R
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Amino acids 76 – 170 of human PUMA-alpha.
- 亚型：
mouse IgG1
- 形态：
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.02% sodium azide. Antibody was purified by Protein-A affinity chromatography.
- 保存条件：
Store at 4°C.
- 克隆性：
单克隆
- 标记物：
见下方详细说明
- 适应物种：
H, R
- 保质期：
1-2年
- 抗原来源：
Amino acids 76 – 170 of human PUMA-alpha.
- 目录编号：
253254
- 级别：
超纯
- 库存：
大量
- 供应商：
Abbiotec
- 宿主：
Mouse
- 应用范围：
E, WB
- 浓度：
见详细说明信息
- 靶点：
PUMA (2A8F6)
- 抗体英文名：
PUMA (2A8F6) Antibody
- 抗体名：
PUMA (2A8F6) Antibody
- 规格：
0.1 mg
PUMA (2A8F6) Antibody产品详细介绍：
| 产品名称： | PUMA (2A8F6) Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 253254 |
| 规格： | 0.1 mg |
| 产品描述： | Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible pro-apoptotic gene was identified recently and designated PUMA (for p53 upregulated modulator of apoptosis) and bbc3 (for Bcl-2 binding component 3) in human and mouse. PUMA/bbc3 is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis. |
| 克隆类型： | Mouse Monoclonal Antibody |
| 亚型： | mouse IgG1 |
| 免疫原： | Amino acids 76 – 170 of human PUMA-alpha. |
| 适用物种： | H, R |
| 应用范围： | E, WB |
| 应用说明： | E: 1:500-1:1,000; WB: 1:100-1:500 |
| 别名： | PUMA; p53 upregulated modulator of apoptosis; bbc3; Bcl-2 binding component 3 |
| 形态： | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.02% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存条件： | Store at 4°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
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文献和实验Whole mount antibody staining of zebrafish embryos for markers of segmentation
, 10 minutes each. 3. Incubate overnight at 4oC (cold room) in 0.5 ml primary antibody in 0.2% saponin in PBS. Primary antibodies: (A) znp-1 @ 1/2000 (primary motoneurons) (B)F6@ 1/500 (somite boundaries) (C) no antibody (Control)
Early development of primary motor neurons and somites in Zebrafish Embryos
hour stage,the technique of whole mount antibody staining will be used. The ZNP-1 antibody will specifically bind to the primary motor neurons. Since ZNP-1 will not bind to the somites, another antibody,F6,will be used to bind to the somite
an important role in regulation of the immune system. In the method described, hepatoma MH134 (Fas− and FasL− ) is transfected with murine Fas and FasL cDNA. A single administration of monoclonal anti-Fas antibody efficiently suppresses the growth of F6b (MH134
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