- ￥3000 - 3999
- Abbiotec
- 美国
- 253254
- 2025年11月10日
- E, WB
- Mouse
- H, R
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Amino acids 76 – 170 of human PUMA-alpha.
- 亚型：
mouse IgG1
- 形态：
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.02% sodium azide. Antibody was purified by Protein-A affinity chromatography.
- 保存条件：
Store at 4°C.
- 克隆性：
单克隆
- 标记物：
见下方详细说明
- 适应物种：
H, R
- 保质期：
1-2年
- 抗原来源：
Amino acids 76 – 170 of human PUMA-alpha.
- 目录编号：
253254
- 级别：
超纯
- 库存：
大量
- 供应商：
Abbiotec
- 宿主：
Mouse
- 应用范围：
E, WB
- 浓度：
见详细说明信息
- 靶点：
PUMA (2A8F6)
- 抗体英文名：
PUMA (2A8F6) Antibody
- 抗体名：
PUMA (2A8F6) Antibody
- 规格：
0.1 mg
PUMA (2A8F6) Antibody产品详细介绍：
| 产品名称： | PUMA (2A8F6) Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 253254 |
| 规格： | 0.1 mg |
| 产品描述： | Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible pro-apoptotic gene was identified recently and designated PUMA (for p53 upregulated modulator of apoptosis) and bbc3 (for Bcl-2 binding component 3) in human and mouse. PUMA/bbc3 is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis. |
| 克隆类型： | Mouse Monoclonal Antibody |
| 亚型： | mouse IgG1 |
| 免疫原： | Amino acids 76 – 170 of human PUMA-alpha. |
| 适用物种： | H, R |
| 应用范围： | E, WB |
| 应用说明： | E: 1:500-1:1,000; WB: 1:100-1:500 |
| 别名： | PUMA; p53 upregulated modulator of apoptosis; bbc3; Bcl-2 binding component 3 |
| 形态： | Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.02% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存条件： | Store at 4°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
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文献和实验Early development of primary motor neurons and somites in Zebrafish Embryos
hour stage,the technique of whole mount antibody staining will be used. The ZNP-1 antibody will specifically bind to the primary motor neurons. Since ZNP-1 will not bind to the somites, another antibody,F6,will be used to bind to the somite
Whole mount antibody staining of zebrafish embryos for markers of segmentation
, 10 minutes each. 3. Incubate overnight at 4oC (cold room) in 0.5 ml primary antibody in 0.2% saponin in PBS. Primary antibodies: (A) znp-1 @ 1/2000 (primary motoneurons) (B)F6@ 1/500 (somite boundaries) (C) no antibody (Control)
an important role in regulation of the immune system. In the method described, hepatoma MH134 (Fas− and FasL− ) is transfected with murine Fas and FasL cDNA. A single administration of monoclonal anti-Fas antibody efficiently suppresses the growth of F6b (MH134
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