- ￥3000 - 3999
- Abbiotec
- 美国
- 252836
- 2025年12月10日
- WB
- Mouse
- H
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Purified recombinant fragment of LAMB1(aa31-270) expressed in E. coli. <br>
- 亚型：
Mouse IgG2a
- 形态：
Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
- 保存条件：
Store at -20°C
- 克隆性：
单克隆
- 标记物：
见下方详细说明
- 适应物种：
H
- 保质期：
1-2年
- 抗原来源：
Purified recombinant fragment of LAMB1(aa31-270) expressed in E. coli. <br>
- 目录编号：
252836
- 级别：
超纯
- 库存：
大量
- 供应商：
Abbiotec
- 宿主：
Mouse
- 应用范围：
WB
- 浓度：
见详细说明信息
- 靶点：
LAMB1 (2D9G)
- 抗体英文名：
LAMB1 (2D9G) Antibody
- 抗体名：
LAMB1 (2D9G) Antibody
- 规格：
0.1 ml
LAMB1 (2D9G) Antibody产品详细介绍：
| 产品名称： | LAMB1 (2D9G) Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 252836 |
| 规格： | 0.1 ml |
| 产品描述： | LAMB1 (Laminin, beta 1) is a major component of the basal lamina. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. The beta 1 chain has 7 structurally distinct domains which it shares with other beta chain isomers. The C-terminal helical region containing domains I and II are separated by domain alpha, domains III and V contain several EGF-like repeats, and domains IV and VI have a globular conformation. Laminin, beta 1 is expressed in most tissues that produce basement membranes, and is one of the 3 chains constituting laminin 1, the first laminin isolated from Engelbreth-Holm-Swarm (EHS) tumor. A sequence in the beta 1 chain that is involved in cell attachment, chemotaxis, and binding to the laminin receptor was identified and shown to have the capacity to inhibit metastasis. |
| 克隆类型： | Mouse Monoclonal Antibody |
| 亚型： | Mouse IgG2a |
| 免疫原： | Purified recombinant fragment of LAMB1(aa31-270) expressed in E. coli. |
| 适用物种： | H |
| 应用范围： | WB |
| 应用说明： | WB: 1:500-1:2000; |
| 别名： | Laminin subunit beta-1; Laminin B1 chain; Laminin-1 subunit beta; Laminin-10 subunit beta; Laminin-12 subunit beta; Laminin-2 subunit beta; Laminin-6 subunit beta; Laminin-8 subunit beta LAMB1 |
| 形态： | Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide. |
| 保存条件： | Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 参考文献： |
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人可溶性白细胞抗原G(sHLA-G)酶联免疫分析（ELISA）
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