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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser892 of rat GABAB receptor, R2-subunit.
- 亚型:
Rabbit Ig
- 形态:
Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
- 保存条件:
Store at -20°C.
- 克隆性:
多克隆
- 标记物:
见下方详细说明
- 适应物种:
B, D, Ck, H, M, X, Zf
- 保质期:
1-2年
- 抗原来源:
KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser892 of rat GABAB receptor, R2-subunit.
- 目录编号:
252544
- 级别:
超纯
- 库存:
大量
- 供应商:
Abbiotec
- 宿主:
Rabbit
- 应用范围:
E, WB
- 浓度:
见详细说明信息
- 靶点:
GABABR2 (Ser892)
- 抗体英文名:
GABABR2 (Ser892) Antibody
- 抗体名:
GABABR2 (Ser892) Antibody
- 规格:
0.1 ml
GABABR2 (Ser892) Antibody产品详细介绍:
| 产品名称: | GABABR2 (Ser892) Antibody |
| 说明书: | 【点击查看详细说明及参考图片】 |
| 货号: | 252544 |
| 规格: | 0.1 ml |
| 产品描述: | Gamma-aminobutyric acid type B receptor subunit 1 (GABA-Receptor, R-2 subunit), together with the GABA-Receptor, R-1 subunit, forms a receptor for GABA. The activity of GABA-B-Receptor is mediated by G-proteins that inhibit adenylyl cyclase activity, stimulate phospholipase A2, activates potassium channels, inactivate voltage-dependent calcium-channels and modulate inositol phospholipids hydrolysis. The GABA-B-Receptor plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA-B-Receptors inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA-B-Receptor decrease neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. The GABA receptor has not only been implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception. Phosphorylation of Ser783 plays a critical role in enhancing neuronal survival after ischemia. |
| 克隆类型: | Rabbit Polyclonal Antibody, Phosphospecific Antibody |
| 亚型: | Rabbit Ig |
| 免疫原: | KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser892 of rat GABAB receptor, R2-subunit. |
| 适用物种: | B, D, Ck, H, M, X, Zf |
| 应用范围: | E, WB |
| 应用说明: | E: 1:1,000; WB: 1:1,000 |
| 别名: | Gamma-aminobutyric acid type B receptor subunit 2; GABA-B receptor 2; GABA-B-R2; GABA-BR2; GABABR2; Gb2; G-protein coupled receptor 51; Gabbr2; Gpr52 |
| 形态: | Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography. |
| 保存条件: | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献: |
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