- ￥1500 - 2500
- HUABIO
- ER1915-84
- 浙江杭州
- 2025年07月11日
- WB
- Rabbit
- Human, Mouse, Rat, Pig, Cow
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- 详细信息
- 文献和实验
- 技术资料
- 靶点：
RGMA
- 浓度：
1 mg/mL.
- 应用范围：
WB
- 宿主：
Rabbit
- 适应物种：
Human, Mouse, Rat, Pig, Cow
- 保质期：
1年
- 供应商：
Huabio
- 标记物：
Non-conjugated
- 保存条件：
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
- 形态：
Liquid
- 亚型：
IgG
- 免疫原：
KLH conjugated synthetic peptide derived from human Repulsive Guidance Molecule A 301-400/1450
- 规格：
50μl/100μl
| 规格： | 50μl | 产品价格： | ￥1500.0 |
|---|---|---|---|
| 规格： | 100μl | 产品价格： | ￥2500.0 |
Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses. Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition. Furthermore, RGMA binding to NEO1/neogenin leads to HRAS inactivation by influencing HRAS1-PTK2/FAK1-AKT1 pathway. It also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, SMAD5, and SMAD8.
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ER1915-84·Anti-RGMA Antibody
￥1500 - 2500
