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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
4°C, protect from light
- 英文名:
Eriodictyol 7-rutinoside; Eriodictyol 7-O-rutinoside
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
13463-28-0
- 规格:
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥1050.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥500.0 |
| 规格: | 5 mg | 产品价格: | ¥800.0 |
| 规格: | 10 mg | 产品价格: | ¥1400.0 |
| 规格: | 25 mg | 产品价格: | ¥2250.0 |
| 规格: | 50 mg | 产品价格: | ¥3600.0 |
| 规格: | 100 mg | 产品价格: | ¥5400.0 |
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Eriocitrin
CAS No. : 13463-28-0
MCE 国际站:Eriocitrin
产品活性:Eriocitrin 是一种从柠檬中分离出来的黄酮类化合物,它是一种强效的抗氧化剂。Eriocitrin 通过上调 p53,cyclin A,cyclin D3 和 CDK6 使 S 期细胞周期停滞,从而抑制肝癌细胞的增殖。Eriocitrin 通过激活线粒体涉及的内在信号传导途径来触发细胞凋亡。
研究领域:Apoptosis
作用靶点:Apoptosis
In Vitro: Eriocitrin (25-75 μM; 24 h) arrests the cell cycle in the S phase, (5-10 μM; 24 h) and inhibits proliferation and focus formation of liver cancer cell lines HepG2 and Huh7.
Eriocitrin (25-75 μM; 12 h) upregulates p53, cyclin A, cyclin D3, and CDK6 levels in HepG2 cells.
Eriocitrin (25-75 μM; 48 h) triggers apoptosis by activating mitochondria-related intrinsic signaling pathways.
In Vivo: Eriocitrin (10-60 mg/kg; ip; once daily, from the day of modeling until the end of the experiment) attenuates acute kidney injury (AKI) induced by ischemia reperfusion (IR) in rats, and reduces renal tissue cell apoptosis, turns its kidney inflammatory response and oxidative stress.
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文献和实验=6~ 18, 21。本科植物的花托,或上位花的子房顶部,或退化雄蕊面向子房的表面,通常分泌蜜汁,引诱昆虫,帮助完成传粉。约 80属, 1200余种,分布极广,几遍全球,主产温带。中国有 28属,约 500种,南北均有分布,主产西南,其中独根草属为中国特有属。 本科多为药用或观赏植物,如落新妇属、岩白菜属、绣球属、鬼灯檠属、虎耳草属等的一些种;常山可治疟疾。 本科主要的亚科、属及常见种有: 扯根菜亚科 仅扯根菜属( Penthorum) 1属,约 2种。分布于亚洲
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