- ￥2260
- LSM Bio
- 进口
- PAab09973
- 2025年07月05日
- ELISA, WB, IHC
- E. coli - derived recombinant protein
- Human, Mouse
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
prostaglandin-endoperoxide synthase 2
- 亚型：
IgG2a
- 形态：
liquid
- 保存条件：
负20摄氏度
- 克隆性：
monoclonal
- 标记物：
Non-conjugated
- 适应物种：
Human, Mouse
- 保质期：
6个月
- 抗原来源：
Mouse
- 目录编号：
Q9BZJ3
- 级别：
纯化级别
- 库存：
50
- 供应商：
LSM bio
- 宿主：
E. coli - derived recombinant protein
- 应用范围：
ELISA, WB, IHC
- 浓度：
≥95% as determined by SDS-PAGE
- 靶点：
prostaglandin-endoperoxide synthase 2
- 抗体英文名：
COX2 antibody
- 抗体名：
COX2 antibody
- 规格：
100μl
COX2 antibody
Product Name COX2 antibody
Catalog No PAab09973
Packing 100ul
Form liquid
Alternative Name COX 2, COX2, Cyclooxygenase 2, GRIPGHS, hCox 2, PGG/HS, PGH synthase 2, PGHS 2, PHS 2, PHS II, Prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, PTGS2
Purification protein A+G purified
Purity 95% as determined by SDS-PAGE
Host Mouse
Isotype IgG2a
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.
Immunogen prostaglandin-endoperoxide synthase 2
Specificity Human, Mouse
Tested Application ELISA, WB, IHC
Recommended dilution WB: 1:500-1:2000; IHC: 1:100-1:400
IHC use Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using PAab09973(COX2 Antibody) at dilution of 1:200
WB use
LPS treated Hela cells were subjected to SDS PAGE followed by western blot with PAab09973(COX2 antibody) at dilution of 1:1000
Protein Information
Gene ID 5743
Uniprot ID P35354
Calculated MW 68 kDa
Research Area Cancer, Cardiovascular, Metabolism
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文献和实验Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
The importance of antibody molecules was first recognized in the 1890s, when it was shown that immunity to tetanus and diphtheria was caused by antibodies against the bacterial exotoxins (1 ). Around the same time, it was shown that antisera
General comments: Antibodies, like most proteins, do not like to be freeze-thawed. Avoid repetitive freezing of your solution. The best way to store your antibody is to keep a high protein concentration (>1 mg/ml), add some protease
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