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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
apolipoprotein E 33B
- 亚型:
IgG
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
polyclonal
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse, Rat
- 保质期:
6个月
- 抗原来源:
Rabbit
- 目录编号:
Q9BZJ3
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA, WB, IHC, IF
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
apolipoprotein E 33B
- 抗体英文名:
APOE antibody
- 抗体名:
APOE antibody
- 规格:
100μl
APOE antibody
Product Name APOE antibody
Catalog No PAab10127
Packing 100ul
Form liquid
Alternative Name APOE, AD2 APO-E ApoE4 LDLCQ5, LPG, apolipoprotein E
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Immunogen apolipoprotein E 33B
Specificity Human, Mouse, Rat
Tested Application ELISA, WB, IHC, IF
Recommended dilution WB: 1:200-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200
IHC use Immunohistochemistry of paraffin-embedded human stomach tissue slide using PAab10127 (APOE Antibody) at dilution of 1:100.
WB use
SKOV3 cells were subjected to SDS PAGE followed by western blot with PAab10127 (APOE antibody) at dilution of 1:1000
Protein Information
Gene ID 348
Uniprot ID P02649
Calculated MW 35 kDa
Research Area
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文献和实验施一公团队 2023 首秀!发现 APOE4 受体,揭示阿尔兹海默症潜在致病因子
导读 APOE 的基因产物 APOE 在脂质代谢、免疫调节和神经学中起着关键作用。最常见的三种 APOE 等位基因对应于三种蛋白质异构体,分别是 APOE2、APOE3 和 APOE4,它们仅在 112 和 158 两个氨基酸位置上存在差异。尽管只存在微小差别,但前期的研究数据表明,这些 APOE 亚型在生理和病理学层面却表现出不同的作用。 其中,APOE 的免疫调节作用最初是作为血浆脂蛋白对 T 细胞增殖抑制作用的一部分被发现的。研究表明,APOE 能够抑制 T 细胞增殖和中
APOE-Based Models of Pre-Dementia
Producing a valid animal model of apolipoprotein E (APOE )-based dementia is critical to understanding the etiology and progression of late-onset Alzheimer’s disease (AD). Unfortunately, no such model exists. Herein, I review
Laser-Capture Microdissection of Hyperlipidemic/ApoE/ Mouse Aorta Atherosclerosis
roles have not been defined. To map these infiltrates, we employed laser-capture microdissection (LCM) to isolate the three arterial wall laminae using apoE−/− mouse aorta as a model. RNA from LCM-separated tissues was extracted and large-scale
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