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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CD80
- 亚型:
IgG1
- 形态:
liquid
- 保存条件:
负20摄氏度
- 克隆性:
monoclonal
- 标记物:
Non-conjugated
- 适应物种:
Human, Mouse
- 保质期:
6个月
- 抗原来源:
Mouse
- 目录编号:
Q9BZJ3
- 级别:
纯化级别
- 库存:
50
- 供应商:
LSM bio
- 宿主:
E. coli - derived recombinant protein
- 应用范围:
ELISA, IHC, WB
- 浓度:
≥95% as determined by SDS-PAGE
- 靶点:
CD80
- 抗体英文名:
CD80 antibody
- 抗体名:
CD80 antibody
- 规格:
100μl
CD80 antibody
Product Name CD80 antibody
Catalog No PAab09813
Packing 100ul
Form liquid
Alternative Name Activation B7 1 antigen, B7, B7 1, B7-1, BB1, CD28LG, CD28LG1, CD80, CD80 molecule, CTLA 4 counter receptor B7.1, LAB7
Purification Protein A+G purification
Purity 95% as determined by SDS-PAGE
Host Mouse
Isotype IgG1
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.
Immunogen CD80
Specificity Human, Mouse
Tested Application ELISA, IHC, WB
Recommended dilution WB: 1:1000-1:4000; IHC: 1:50-1:500
IHC use Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using PAab09813(CD80 antibody)at dilution of 1:200
WB use
Raji cells were subjected to SDS PAGE followed by western blot with PAab09813(CD80 antibody) at dilution of 1:2000
Protein Information
Gene ID
Uniprot ID P33681
Calculated MW 74 kDa
Research Area Immunology,
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文献和实验CD80 分子 CD80 常用单克隆抗体或代号: B7- 1,BB1 主要表达细胞: Ba,Mac,TStr [B] 分子质量(kDa)和结构: gp60(IgSF) 功 能: 活化B细胞抗原,CD28、CTLA- 4配体,提供T细胞共刺激信号 CD80 Aka B7-1, BB1 Ligand for T cell marker CD28 or CTLA4 (CD152
Generation of Antibody Molecules Through Antibody Engineering
been overcome to a large extent using genetic-engineering techniques to produce chimeric mouse/human and completely human antibodies. Such an approach is particularly suitable because of the domain structure of the antibody molecule ( 2 ), where functional
Non-Replicating Recombinant Vaccinia Virus Expressing CD80 to Enhance T-Cell Stimulation
The following method describes the generation of a recombinant vaccinia virus expressing a costimulatory molecule (human CD80 or B7.1). The procedure first requires the cloning, by classical methods not described here, of the gene
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