Vinculin antibody
Product Name Vinculin antibody
Catalog No PAab09799
Packing 100ul
Form liquid
Alternative Name CMD1W, Metavinculin, MVCL, VCL, Vinculin
Purification Immunogen affinity purified
Purity 95% as determined by SDS-PAGE
Host Rabbit
Isotype IgG
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20Centigrade for 24 months (Avoid repeated freeze / thaw cycles.)
Background/ FUNCTION
Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
Immunogen vinculin
Specificity Human, Mouse, Rat
Tested Application ELISA, IHC, WB
Recommended dilution WB: 1:500-1:2000; IHC: 1:50-1:200
IHC use Immunohistochemistry of paraffin-embedded human prostate cancer tissue slide using PAab09799( Vinculin Antibody) at dilution of 1:100
WB use
HepG2 cells were subjected to SDS PAGE followed by western blot with PAab09799(Vinculin Antibody) at dilution of 1:1000
Protein Information
Gene ID 7414
Uniprot ID P18206
Calculated MW 124 kDa
Research Area Immunology, Cardiovascular