产品货号:jlcR12760 英文名称 :VOPP1 中文名称 :EGFR扩增和过度表达蛋白抗体 别 名 :ECop; EGFR-coamplified and overexpressed protein; GASP; Glioblastoma-amplified secreted protein; overexpressed in cancer; prosurvival protein 1; Putative NF-kappa-B-activating protein 055N; Vesicular; Vesicular, overexpressed in cancer, prosurvival protein 1; vopp1; VOPP1_HUMAN. 研究领域 :肿瘤 细胞生物 细胞凋亡 转录调节因子 表观遗传学 抗体来源 :Rabbit 克隆类型 :Polyclonal 交叉反应 : Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, 产品应用 :ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分 子 量 :17kDa 细胞定位 :细胞浆 性 状 :Lyophilized or Liquid 浓 度 :1mg/ml 免 疫 原 :KLH conjugated synthetic peptide derived from human VOPP1:41-140/172 <Cytoplasmic> 亚 型 :IgG 纯化方法 :affinity purified by Protein A 储 存 液 :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 :Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed :PubMed 产品介绍 :VOPP1 (Vesicular, Overexpressed In Cancer, Prosurvival Protein 1) is a Protein Coding gene. GO annotations related to this gene include signal transducer activity.
Function: Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed.
Subcellular Location: Cytoplasmic vesicle membrane. When overexpressed, localizes in the nucleus and perinuclear regions.
Tissue Specificity: Widely expressed with highest levels in thymus and ovary.
Similarity: Belongs to the VOPP1/ECOP family.
SWISS: Q96AW1
Gene ID: 81552
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.