Recombinant Human CD80 / B7-1 Protein (ECD, Fc Tag)
库存:
99
供应商:
北京义翘神州科技股份有限公司
规格:
100 µg/1 mg
规格:
100 µg
产品价格:
¥2570.0
规格:
1 mg
产品价格:
¥16740.0
重组人 CD80 / B7-1 蛋白 (ECD, Fc标签)(产品说明)
蛋白名称:Human CD80 / B7-1 Protein (ECD, Fc Tag)
蛋白构建:A DNA sequence encoding the human CD80 (NP_005182.1) (Met1-Asn242) was expressed with the Fc region of human IgG1 at the C-terminus.
表达宿主:HEK293 Cells
蛋白纯度:> 95 % as determined by SDS-PAGE.
蛋白活性:0
蛋白内毒素:< 1.0 EU per μg protein as determined by the LAL method.
预测N端:Val 35
蛋白分子量:The recombinant human CD80 consists of 446 amino acids and predicts a molecular mass of 50.6 kDa. As a result of glycosylation, it migrates as an approximately 65.8 kDa band in SDS-PAGE under reducing conditions.
蛋白NP号:NP_005182.1
蛋白氨基酸序列:Met1-Asn242
蛋白标签:C-human IgG1-Fc
蛋白保存条件:Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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2, Xu, X; et al. CTLA4 depletes T cell endogenous and trogocytosed B7 ligands via cis-endocytosis. The Journal of experimental medicine, Pubmed: 37042938
3, Liu, M; et al. Soluble CTLA-4 mutants ameliorate immune-related adverse events but preserve efficacy of CTLA-4- and PD-1-targeted immunotherapy. Science translational medicine, Pubmed: 36857433
4, Xu, Y; et al. A VEGFR2-MICA bispecific antibody activates tumor-infiltrating lymphocytes and exhibits potent anti-tumor efficacy in mice. Cancer Immunol. Immunother., Pubmed: 31428800