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- 详细信息
- 技术资料
- 供应商:
PeproTech(派普泰克)
- 库存:
大量
- 英文名:
Recombinant Human 4-1BB Ligand
- 规格:
5ug/20ug/100ug/250ug/500ug/1000ug
Animal-Free Recombinant Human 4-1BB Ligand
Product Details
Catalog Number:AF-310-11Description:
4‐1BBL, a member of the TNF superfamily, is expressed in B cells, dendritic cells, activated T cells and
macrophages. 4‐1BBL binds to its receptor 4‐1BB, and provides a co‐stimulatory signal for T cell activation and expansion. The human 4‐1BBL gene codes for a 254 amino acid type II transmembrane protein containing a 28 amino acid cytoplasmic domain, a 21 amino acid transmembrane protein domain, and a 205 amino acid extracellular domain. The soluble form of 4‐1BBL contains the TNF‐like portion of the extracellular domain of 4‐1BBL. Recombinant Human 4‐1BB Ligand is a soluble 19.5 kDa protein consisting of 185 amino acid residues.
Manufactured using all Animal-Free reagents.
Source:E.coli
Synonyms:TNFSF9, CD137L
AA Sequence:MREGPELSPD DPAGLLDLRQ GMFAQLVAQN VLLIDGPLSW YSDPGLAGVS LTGGLSYKED TKELVVAKAG VYYVFFQLEL RRVVAGEGSG SVSLALHLQP LRSAAGAAAL ALTVDLPPAS SEARNSAFGF QGRLLHLSAG QRLGVHLHTE ARARHAWQLT QGATVLGLFR VTPEIPAGLP SPRSE
Purity:≥ 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity:Determined by its ability to induce CD137/NF-κB activation in HEK293 reporter cells.
Country Of Origin: USA
Not for human use.
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