产品货号 : jlcR9629 英文名称 : C16orf7 中文名称 : 16号染色体开放阅读框7抗体 别 名 : ATP BL; C16orf7; Chromosome 16 open reading frame 7; CP007_HUMAN; Protein ATP-BL; Uncharacterized protein C16orf7. 研究领域 : 肿瘤 细胞生物 免疫学 神经生物学 抗体来源 : Rabbit 克隆类型 : Polyclonal 交叉反应 : Human, Mouse, Rat, Cow, 产品应用 : WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分 子 量 : 69kDa 细胞定位 : 细胞核 细胞浆 性 状 : Lyophilized or Liquid 浓 度 : 1mg/ml 免 疫 原 : KLH conjugated synthetic peptide derived from human C16orf7/ATP-BL :25-130/631 亚 型 : IgG 纯化方法 : affinity purified by Protein A 储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed : PubMed 产品介绍 : Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.
Subcellular Location: Ubiquitous.
Similarity: Contains 1 VPS9 domain.
SWISS: Q9Y2B5
Gene ID: 9605
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.