产品货号:jlcR18439 英文名称 : LSS/OSC 中文名称 :2,3-环氧角鲨烯羊毛固醇环化酶抗体 别 名 : 2,3 epoxysqualene lanosterol cyclase; hOSC; ERG7_HUMAN; Lanosterol synthase (2,3 oxidosqualene lanosterol cyclase); Lanosterol synthase; OSC; Oxidosqualene lanosterol cyclase. 研究领域 :肿瘤 细胞生物 免疫学 信号转导 抗体来源 :Rabbit 克隆类型 : Polyclonal 交叉反应 : Human, Mouse, Rat, Rabbit, 产品应用 :ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分 子 量 :83kDa 细胞定位 :细胞浆 性 状 :Lyophilized or Liquid 浓 度 :1mg/ml 免 疫 原 :KLH conjugated synthetic peptide derived from human LSS/OSC:351-450/732 亚 型 :IgG 纯化方法 :affinity purified by Protein A 储 存 液 :0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed :PubMed 产品介绍 : The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2009]
Function: Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus.
Similarity: Belongs to the terpene cyclase/mutase family. Contains 4 PFTB repeats.
SWISS: P48449
Gene ID: 4047
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.