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- 2025年12月05日
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- 文献和实验
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- 保存条件：
-20°C, sealed storage, away from moisture and light
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
18133-22-7
- 规格：
1 mg
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Netropsin dihydrochloride
CAS No. : 18133-22-7
MCE 国际站：Netropsin dihydrochloride
产品活性：Netropsin dihydrochloride 是一种小分子(MGB) 小沟结合剂，抑制分离的拓扑异构酶的催化活性，并干扰拓扑异构酶 II 和 I 在细胞核中的可降解复合物的稳定性。Netropsin dihydrochloride 对牛痘病毒具有抗病毒活性。
研究领域：Cell Cycle/DNA Damage | Anti-infection
作用靶点：DNA/RNA Synthesis | Bacterial | Influenza Virus | Antibiotic | Orthopoxvirus
In Vitro: Netropsin dihydrochloride has potential antibiotic and antiviral properties by binding to dsDNA in a non-intercalative manner, it improves survival from murine endotoxaemia by attenuating NOS2 induction through interference with HMGA1 DNA binding to the core NOS2 promoter.
Netropsin dihydrochloride in solutions of DNA has radioprotective ability against radiation-induced damage due to its high binding affinity and high structural stabilization, hydroxyl radical (OH*) generated by ionizing radiation cannot radiolyse the netropsin-DNA complex.
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文献和实验液配方：碘化钾4g，碘2g，蒸馏水100ml。 3)隐孢子虫卵囊染色检查：目前较佳的方法为金胺酚改良抗酸染色法。对于新鲜粪便或经10%福尔马林固定保存(4℃1个月内)的含卵囊粪便都可用此法染色。染色过程是先用金胺-酚染色，再用改良抗酸染色法复染。方法步骤如下： 金胺-酚染色法： ①染液配制：1g/L金胺-酚染色液(第一液)：金胺0.1g，石碳酸5.0g，蒸馏水100ml；3%盐酸酒精(第二液)：盐酸3ml，95%酒精100ml；5g/L高锰酸钾液(第三液
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