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- 保存条件:
4°C, protect from light
- 英文名:
11-Keto-β-boswellic acid
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
17019-92-0
- 规格:
10 mM * 1 mL/1 mg/5 mg/10 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥1408.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥560.0 |
| 规格: | 5 mg | 产品价格: | ¥1360.0 |
| 规格: | 10 mg | 产品价格: | ¥2160.0 |
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11-Keto-beta-boswellic acid
CAS No. : 17019-92-0
MCE 国际站:11-Keto-beta-boswellic acid
产品活性:11-Keto-beta-boswellic acid (11-Keto-β-boswellic acid) 是一种五环三萜酸,来自俗称印度乳香 (Indian Frankincense) 的乳香树 (Boswellia serrate) 树皮的油树脂。 11-Keto-beta-boswellic acid 具有抗炎活性,主要是由于抑制 5-脂氧合酶 (5-lipoxygenase; 5-LOX),白三烯 (leukotriene),NF-κB的激活和肿瘤坏死因子 α 的产生。
研究领域:Metabolic Enzyme/Protease | GPCR/G Protein | NF-κB
作用靶点:Lipoxygenase | Leukotriene Receptor | NF-κB
In Vitro: 11-Keto-beta-boswellic acid inhibits DPP-4 activity with an IC50 of 1.65 µM.
11-Keto-beta-boswellic acid (10 min) inhibits 4-aminopyridine-stimulated glutamate release in rat hippocampal nerve terminals (IC50: 31 μM).
In Vivo: 11-Keto-beta-boswellic acid (1-10 mg/kg, p.o., for 21 days) shows anti-diabetic activity in Streptozotocin (HY-13753)-induced diabetic rats.
11-Keto-beta-boswellic acid (10 or 50 mg/kg, i.p.) protects rats against Kainic acid (HY-N2309) (15 mg/kg, i.p.)-induced excitotoxicity.
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