- ￥600 - 4200
- MedChemExpress(MCE)
- 美国
- HY-N0047
- 2025年12月05日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
50773-41-6
- 规格：
10 mM * 1 mL/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥941.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥600.0 |
| 规格： | 10 mg | 产品价格： | ￥1000.0 |
| 规格： | 25 mg | 产品价格： | ￥1800.0 |
| 规格： | 50 mg | 产品价格： | ￥2700.0 |
| 规格： | 100 mg | 产品价格： | ￥4200.0 |
MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。
Polyphyllin I
CAS No. : 50773-41-6
MCE 国际站：Polyphyllin I
产品活性：Polyphyllin I 是一种从 Paris polyphylla 中提取的生物活性成分，具有很强的抗肿瘤活性。Polyphyllin I 是 JNK 信号通路的激活剂，也是 PDK1/Akt/mTOR 信号传导的抑制剂。Polyphyllin I 诱导自噬，G2/M 期阻滞和细胞凋亡。
研究领域：MAPK/ERK Pathway | PI3K/Akt/mTOR | Autophagy | Apoptosis
作用靶点：JNK | mTOR | Akt | PDK-1 | Autophagy | Apoptosis
In Vitro: Polyphyllin I (0.625-10 mg/mL; 24-72 h) inhibits the proliferation of three non-small cell lung cancer (NSCLC) cell lines, with the IC50s of 1.24, 2.40, and 2.33 μg/ml for A549, H460, and SK-MES-1 cells, respectively.
Polyphyllin I (2.5 mg/mL; 6-24 h) induces apoptosis of A549 cells.
Polyphyllin I (0.25-2 μM; 24 h) increase in LC3-II expression and decrease in P62 expression in HGC-27 cells.
In Vivo: Polyphyllin I (1.5 mg/kg; i.p. twice daily from day 2 to day 11) significantly inhibit the tumor growth of A549 cells in the nude mice.
相关产品：Natural Product Library Plus | Bioactive Compound Library Plus | Apoptosis Compound Library | Immunology/Inflammation Compound Library | Kinase Inhibitor Library | MAPK Compound Library | PI3K/Akt/mTOR Compound Library | Stem Cell Signaling Compound Library | Natural Product Library | Anti-Cancer Compound Library | Autophagy Compound Library | Anti-Aging Compound Library | Antioxidant Compound Library | Differentiation Inducing Compound Library | Reprogramming Compound Library | Glycoside Compound Library | Lipid Compound Library | Oxygen Sensing Compound Library | Medicine Food Homology Compound Library | Glycolysis Compound Library | Cytoskeleton Compound Library | Glutamine Metabolism Compound Library | Traditional Chinese Medicine Active Compound Library | Anti-Breast Cancer Compound Library | Anti-Lung Cancer Compound Library | Anti-Pancreatic Cancer Compound Library | Anti-Blood Cancer Compound Library | Anti-Cancer Metabolism Compound Library | Anti-Obesity Compound Library | Angiogenesis-Related Compound Library | Transcription Factor-Targeted Library | Glucose Metabolism Compound Library | Anti-Liver Cancer Compound Library | Anti-Colorectal Cancer Compound Library | Anti-Cancer Natural Product Library | Anti-inflammatory Traditional Chinese Medicine Active Compound Library | Plant-Sourced Natural Product Library | Anti-Prostate Cancer Compound Library | Anti-Pulmonary Fibrosis Compound Library | Osteogenesis Compound Library | Cancer Stem Cells Compound Library | Pain-Related Compound Library | Mitochondrial Protection Compound Library | Membrane Protein-targeted Compound Library | Cell Death Library | Serine/Threonine Kinase Inhibitor Library | MG-132 | Rapamycin | Doxorubicin hydrochloride | Bafilomycin A1 | LY294002 | Tamoxifen | Paclitaxel | Y-27632 | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Staurosporine | SB-431542 | Actinomycin D | Deferoxamine mesylate | Bortezomib | 5-Fluorouracil | Trametinib | Sorafenib | Oxaliplatin | Gemcitabine | Temozolomide | Rotenone | Mdivi-1 | Elesclomol | Ruxolitinib | Decitabine | SP600125 | MK-2206 dihydrochloride | Etoposide
热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
