Dulaglutide度拉糖肽,923950-08-7

Dulaglutide

MCE 国际站：Dulaglutide

产品活性：Dulaglutide (LY2189265) 是胰高血糖素样肽-1 (GLP-1) 受体激动剂。

研究领域：GPCR/G Protein

作用靶点：Glucagon Receptor

In Vivo: Dulaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist. No specific Dulaglutide-related cause of death is identified. Survival is numerically increased for both genders of animals in all Dulaglutide treatment groups and reaches statistical significance (P≤0.05) in the 0.5- and 5-mg/kg males and in the 0.05-, 0.5-, and 1.5-mg/kg females. Mean times to peak plasma concentration values of Dulaglutide are observed at 12 hours after dosing on day 1 and rang between 12 and 48 hours at week 52. The incidence of thyroid C-cell adenoma is significantly (P≤0.05) increased compare with controls in males and females at the Dulaglutide 0.5-, 1.5-, and 5-mg/kg doses.

相关产品：Exendin-4  |  Liraglutide  |  Glucagon  |  Adomeglivant  |  Avexitide  |  MK 0893  |  GLP-1(7-36) Acetate  |  GLP-1(7-37)  |  Lixisenatide  |  LGD-6972  |  Semaglutide TFA  |  BETP  |  GRA Ex-25  |  Taspoglutide  |  GLP-1 moiety from Dulaglutide  |  GLP-1 receptor agonist 1  |  FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS  |  GLP-1 receptor agonist 2  |  GLP-2(1-33)(human)  |  Glucagon receptor antagonists-1  |  GTFTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS  |  PF-06291874  |  Glucagon receptor antagonists-2  |  HAEGTFT  |  HAEGTFTSD  |  HAEGTFTSDVS  |  KQMEEEAVRLFIEWLKNGGPSSGAPPPS

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